Impact of supplementation with folic acid on blood pressure in patient with essential hypertension - Trial PACTR202011602578460
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Study Focus
drug
Sponsor & Location
University of Gezira
Mustafa Saleh Saeed
Timeline & Enrollment
Not Applicable
Jun 16, 2020
Dec 30, 2020
Summary
Hypertension is a common global health problem in many countries including Sudan. In the year 2000, more than 25% of the world's population was estimated to have hypertension. This percentage is expected to increase to around 30% by the year 2025. In 2010, the global prevalence of hypertension among adults aged ≥ 20 years was estimated to be 31.1%. In addition to that, the proportion of worldwide morbid complications due to hypertension has significantly increased from approximately 4.5 % in 2000 to 7 % in 2010 which makes hypertension the most important cause of morbidity and mortality globally. In Sudan, the prevalence of hypertension was increased from > 20% in the year 2000 to 35 - < 40 % in the year 2010. In the urban communities of Sudan, the prevalence of hypertension has increased from 7.5% in 1990 to 18.2% in 2002. The Seventh Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) has defined hypertension was as a systolic BP >140 mm Hg, a diastolic BP > 90 mm Hg. This study aims to evaluate the impact of folic acid plus antihypertensive medications compared with antihypertensive medications alone on lowering blood pressure in patients with primary hypertension.
ICD-10 Classifications
Data Source
Pan Africa Clinical Trials Registry
PACTR202011602578460
Non-Device Trial