Effect of isoflurane on diastolic dysfunction - Trial PACTR201701001983201
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Study Focus
other
Sponsor & Location
Fayoum University hospital
Timeline & Enrollment
Not Applicable
Feb 01, 2017
Jan 01, 1900
Summary
Diastolic dysfunction has been increasingly recognized as an important cause of congestive heart failure(CHF) and resultant mortality and morbidity. About 50% patients with CHF have ¿diastolic heart failure¿ in spite of a normal systolic function with preserved ejection fraction. Patients with ischemic heart disease, hypertrophic cardiomyopathy and systemic hypertension may have signs of CHF due to diastolic dysfunction in the absence of preceding impairment of systolic function. Diastolic dysfunction is highly predictive of adverse events after myocardial infarction. Determination of the suitable depth of anesthesia for patients with diastolic dysfunction will decrease the perioperative morbidity, mortality and hospital stay.In this study we will evaluate the effect of depth of anesthesia by isoflurane on left ventricular diastolic function in patients with impaired left ventricular relaxation due to ischemic heart disease undergoing on pump coronary artery bypass graft surgery using transesophageal Doppler echocardiography.
ICD-10 Classifications
Data Source
Pan Africa Clinical Trials Registry
PACTR201701001983201
Non-Device Trial