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Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients - Trial NCT06354452

Access comprehensive clinical trial information for NCT06354452 through Pure Global AI's free database. This phase not specified trial is sponsored by Hospital de Granollers and is currently Completed. The study focuses on Sepsis,Septic Shock. Target enrollment is 59578 participants.

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NCT06354452
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Trial Details
ClinicalTrials.gov โ€ข NCT06354452
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Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients
Preadmission Use of Statin Therapy and Sepsis-related Mortality in ICU Patients: a Population-based Cohort Study.

Study Focus

Sepsis,Septic Shock

Person-level linkage of the database looking for relationship with sepsis survival and previous intake of certain drug families and previous dependence on health services.

Observational

other

Sponsor & Location

Hospital de Granollers

Granollers, Spain

Timeline & Enrollment

N/A

Jan 01, 2018

Jan 31, 2020

59578 participants

Primary Outcome

Death due to sepsis

Summary

The average age of patients with sepsis has increased in recent years in parallel with the
 incidence of sepsis. Many of these patients are frail and require various medications for the
 treatment of their chronic diseases. Common treatments, including e.g. sarcopenic drugs
 (statins, sulphonylureas, methyglinides), antioxidants that prevent sarcopenia (allopurinol)
 or immunoregulators (corticosteroids) may influence the survival and functional prognosis of
 these patients. Knowing which drugs influence sepsis survival and to what degree patients who
 survive sepsis have functional deterioration and increased comorbidity and which modifiable
 factors limit this may be essential.

ICD-10 Classifications

Septic shock
Other sepsis
Other specified sepsis
Sepsis, unspecified
Sepsis due to other specified staphylococcus

Data Source

ClinicalTrials.gov

NCT06354452

Non-Device Trial