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A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS) - Trial NCT06215755

Access comprehensive clinical trial information for NCT06215755 through Pure Global AI's free database. This Phase 1 trial is sponsored by Verge Genomics and is currently Recruiting. The study focuses on Amyotrophic Lateral Sclerosis. Target enrollment is 50 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06215755
Phase 1
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06215755
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A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)
A Phase 1b, Open-Label, Multiple Ascending Dose, Multicenter Study of VRG50635 in Participants With Sporadic and Familial Amyotrophic Lateral Sclerosis Followed by Long-Term Treatment

Study Focus

VRG50635

Interventional

drug

Sponsor & Location

Verge Genomics

Montreal,Utrecht, Canada,Netherlands

Timeline & Enrollment

Phase 1

Jan 15, 2024

Jun 01, 2026

50 participants

Primary Outcome

Number of Participants with Treatment-emergent Adverse Events (TEAEs),Number of Participants with Clinical Laboratory Evaluation Abnormalities,Number of Participants with Vital Sign Abnormalities,Number of Participants with Electrocardiogram (ECG) Abnormalities,Number of Participants with Physical Examination Abnormalities,Number of Participants with Neurological Examination Abnormalities

Summary

The primary purpose of this study is to evaluate the safety and tolerability of VRG50635 in
 participants with ALS.

ICD-10 Classifications

Neuralgic amyotrophy
Motor neuron disease
Other degenerative diseases of the nervous system
Other degenerative disorders of nervous system in diseases classified elsewhere
Multiple sclerosis

Data Source

ClinicalTrials.gov

NCT06215755

Non-Device Trial