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Adjuvant Radiotherapy and Combined Adjuvant Treatment Strategy for UTUC - Trial NCT06120374

Access comprehensive clinical trial information for NCT06120374 through Pure Global AI's free database. This phase not specified trial is sponsored by Peking University First Hospital and is currently Recruiting. The study focuses on Urothelial Carcinoma. Target enrollment is 300 participants.

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NCT06120374
Recruiting
radiation
Trial Details
ClinicalTrials.gov โ€ข NCT06120374
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Adjuvant Radiotherapy and Combined Adjuvant Treatment Strategy for UTUC
Safety and Efficacy of Adjuvant Radiotherapy and Combined Adjuvant Treatment Strategy for Upper Tract Urothelial Carcinoma: An Ambispective Cohort Study

Study Focus

Urothelial Carcinoma

Radiotherapy

Observational

radiation

Sponsor & Location

Peking University First Hospital

Beijing,Beijing,Beijing, China

Timeline & Enrollment

N/A

Oct 30, 2023

Oct 30, 2028

300 participants

Primary Outcome

PFS

Summary

This study is an ambispective cohort observational study to analyze the efficacy of surgery
 alone versus postoperative adjuvant therapy (postoperative radiotherapy/postoperative
 chemotherapy(immunotherapy)/ combined strategy) in patients with the upper urinary tract
 urothelial carcinoma with high-risk factors (postoperative pathology suggestive of pT2 and
 above, N+, G3/high-grade and multiple tumors, positive cut margins). A subgroup analysis was
 performed to obtain the population of patients who might benefit from different treatment
 approaches. Patients with high risk factors for postoperative recurrence or metastasis will
 be treated with relevant adjuvant therapy, which in turn will benefit patients.

ICD-10 Classifications

Carcinoma in situ: Other and unspecified urinary organs
Malignant neoplasm of ureter
Malignant neoplasms of urinary tract
Malignant neoplasm: Overlapping lesion of urinary organs
Malignant neoplasm: Urethra

Data Source

ClinicalTrials.gov

NCT06120374

Non-Device Trial