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Disitamab Vedotin Combined With Radiotherapy for Bladder Preservation - Trial NCT05912205

Access comprehensive clinical trial information for NCT05912205 through Pure Global AI's free database. This Phase 2 trial is sponsored by Wuhan Union Hospital, China and is currently Not yet recruiting. The study focuses on Urothelial Carcinoma. Target enrollment is 30 participants.

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NCT05912205
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT05912205
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Disitamab Vedotin Combined With Radiotherapy for Bladder Preservation
An Open, Single Arm, Phase II Clinical Study on the Efficacy and Safety of Bladder Sparing Therapy With Vidixizumab Combined With Local Radiotherapy in Patients With HER-2 Expressing Myometrial Invasive Urothelium Carcinoma

Study Focus

Urothelial Carcinoma

Disitamab Vedotin

Interventional

drug

Sponsor & Location

Wuhan Union Hospital, China

Timeline & Enrollment

Phase 2

Jul 01, 2023

Jul 01, 2026

30 participants

Primary Outcome

Bladder-intact event-free survival

Summary

This is a prospective, open, single center clinical study of vidicizumab combined with local
 radiotherapy as bladder conserving therapy in patients with muscle invasive bladder
 urothelium cancer with HER-2 expression (IHC 2+or 3+). A total of 30 subjects were included
 in the study

ICD-10 Classifications

Carcinoma in situ: Other and unspecified urinary organs
Malignant neoplasm of ureter
Malignant neoplasms of urinary tract
Malignant neoplasm: Overlapping lesion of urinary organs
Malignant neoplasm: Urethra

Data Source

ClinicalTrials.gov

NCT05912205

Non-Device Trial