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A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract - Trial NCT05868265

Access comprehensive clinical trial information for NCT05868265 through Pure Global AI's free database. This Phase 2 trial is sponsored by Memorial Sloan Kettering Cancer Center and is currently Recruiting. The study focuses on Urothelial Carcinoma. Target enrollment is 24 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT05868265
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT05868265
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A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract
Neoadjuvant Enfortumab Vedotin in High-Grade Urothelial Carcinoma of the Upper Urinary Tract (Including Ureter and Renal Pelvis)

Study Focus

Urothelial Carcinoma

Enfortumab Vedotin

Interventional

drug

Sponsor & Location

Memorial Sloan Kettering Cancer Center

Basking Ridge,Middletown,Montvale,Commack,Harrison,New York,Uniondale, United States of America

Timeline & Enrollment

Phase 2

Jun 02, 2023

May 01, 2025

24 participants

Primary Outcome

Proportion of patients who achieve pathologic complete response

Summary

The purpose of this study is to find out whether the study drug, enfortumab vedotin, is an
 effective and safe treatment for people who have urothelial carcinoma of the upper urinary
 tract. Study participants will be people who are not eligible to receive or have chosen not
 to receive the chemotherapy drug cisplatin for treatment of their cancer. In addition, all
 participants will be planning on having standard surgery to remove their tumor.

ICD-10 Classifications

Carcinoma in situ: Other and unspecified urinary organs
Malignant neoplasm of ureter
Malignant neoplasms of urinary tract
Malignant neoplasm: Overlapping lesion of urinary organs
Malignant neoplasm: Urethra

Data Source

ClinicalTrials.gov

NCT05868265

Non-Device Trial