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SGLT2 Inhibitor for Severe Tricuspid Regurgitation - Trial NCT05686616

Access comprehensive clinical trial information for NCT05686616 through Pure Global AI's free database. This phase not specified trial is sponsored by Samsung Medical Center and is currently Recruiting. The study focuses on Tricuspid Regurgitation. Target enrollment is 72 participants.

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NCT05686616
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Trial Details
ClinicalTrials.gov โ€ข NCT05686616
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SGLT2 Inhibitor for Severe Tricuspid Regurgitation
Multicenter, Randomized, Controlled Trial to Assess the Efficacy of Sodium Glucose Cotransporter-2 Inhibitor add-on Treatment in Patients With Severe Tricuspid Regurgitation

Study Focus

Tricuspid Regurgitation

Dapagliflozin Propanediol Hydrate 12.3 mg

Interventional

drug

Sponsor & Location

Samsung Medical Center

Seoul, South Korea

Timeline & Enrollment

N/A

Apr 13, 2022

Mar 03, 2025

72 participants

Primary Outcome

Difference of RVESVi by CMR from baseline to 12 months follow-up (โˆ†RVESVi)

Summary

The purpose of this study to identify the efficacy of sodium glucose cotransporter 2
 inhibitors add-on treatment on right ventricular remodeling and the amount of severe
 tricuspid regurgitation (TR) in patients with isolated severe TR.

ICD-10 Classifications

Tricuspid stenosis
Tricuspid stenosis with insufficiency
Nonrheumatic tricuspid (valve) stenosis
Tricuspid insufficiency
Nonrheumatic tricuspid (valve) stenosis with insufficiency

Data Source

ClinicalTrials.gov

NCT05686616

Non-Device Trial