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A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure - Trial NCT05659264

Access comprehensive clinical trial information for NCT05659264 through Pure Global AI's free database. This Phase 1 trial is sponsored by ModernaTX, Inc. and is currently Recruiting. The study focuses on Chronic Heart Failure. Target enrollment is 98 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT05659264
Phase 1
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT05659264
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A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
A Phase 1, Adaptive, Open-Label, Single Ascending Dose to Single-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-0184 in Participants With Chronic Heart Failure

Study Focus

Chronic Heart Failure

mRNA-0184

Interventional

drug

Sponsor & Location

ModernaTX, Inc.

Wroclaw,Lรณdz,Bialystok,Katowice,Dundee,Plymouth, Poland,United Kingdom

Timeline & Enrollment

Phase 1

Nov 18, 2022

May 07, 2024

98 participants

Primary Outcome

Number of Participants With Treatment-Emergent Adverse Events (TEAEs)

Summary

The primary objective of this study is to evaluate the safety and tolerability of single and
 multiple doses at escalating dose levels of mRNA-0184.

ICD-10 Classifications

Heart failure
Heart failure, unspecified
Congestive heart failure
Hypertensive heart disease with (congestive) heart failure
Hypertensive heart disease without (congestive) heart failure

Data Source

ClinicalTrials.gov

NCT05659264

Non-Device Trial