Developing an Objective Measure of Experienced Pain - Trial NCT05415423

Timeline & Enrollment

Primary Outcome

Choices between monetary amounts and painful stimuli,self-reported pain ratings according to Numerical Rating Scale (NRS),self-reported pain ratings according to Visual Analogue Scale (VAS),self-reported pain ratings according to general Labeled Magnitude Scale (gLMS),response times

Summary

Pain is a public health challenge around the world. However, there is no single standardized
 measure of pain, to the point that the estimated prevalence of chronic pain in adults ranges
 between 2% and 64% depending on the methods and definitions used. Existing measures of pain
 are known to present several problems and results can be hardly compared between people.
 
 The investigators propose and empirically validate a new, simple method to measure
 experienced pain in clinical trials. The method provides an objective, cardinal measurement
 of experienced pain which is comparable between people and the investigators test whether it
 is better able to measure experienced pain than existing procedures. The investigators test
 the new method in healthy participants using standard protocols (electrical and heat
 stimuli). The investigators also aim to validate the measure using a causal manipulation
 which relies on the administration of a topical analgesic product compared to a placebo.

ICD-10 Classifications