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Interaction of Volatile Anesthetics With Magnesium - Trial NCT05261516

Access comprehensive clinical trial information for NCT05261516 through Pure Global AI's free database. This Phase 4 trial is sponsored by Christoph Czarnetzki and is currently Not yet recruiting. The study focuses on Neuromuscular Blockade. Target enrollment is 96 participants.

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NCT05261516
Phase 4
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT05261516
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Interaction of Volatile Anesthetics With Magnesium
Interaction Between Intravenous Magnesium Sulfate and Volatile Anesthetics Compared to Propofol. A Three-center Prospective Randomized Single-blinded Electrophysiological Study

Study Focus

Neuromuscular Blockade

Magnesium Sulfate

Interventional

drug

Sponsor & Location

Christoph Czarnetzki

University Hospital, Geneva

Genรจve,Lugano,Sion, Switzerland

Timeline & Enrollment

Phase 4

Mar 15, 2022

Mar 15, 2024

96 participants

Primary Outcome

Change in TOF ratio after perfusion of magnesium

Summary

Magnesium and volatiles anesthetics both have an effect on the neuromuscular transmission.
 The primary objective of the study is to quantify the effect of a perfusion of intravenous
 magnesium on neuromuscular transmission measured by acceleromyography with the TofScan device
 in patients undergoing general anesthesia with volatile anesthetics (desflurane, sevoflurane
 and isoflurane) as compared to intravenous anesthesia with propofol.

ICD-10 Classifications

Skeletal muscle relaxants [neuromuscular blocking agents]
Poisoning: Skeletal muscle relaxants [neuromuscular blocking agents]
Other neuromuscular dysfunction of bladder
Neuromuscular dysfunction of bladder, unspecified
Neuromuscular scoliosis

Data Source

ClinicalTrials.gov

NCT05261516

Non-Device Trial