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The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular Events - Trial NCT04646252

Access comprehensive clinical trial information for NCT04646252 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Athens and is currently Recruiting. The study focuses on Endothelial Dysfunction. Target enrollment is 500 participants.

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NCT04646252
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Trial Details
ClinicalTrials.gov โ€ข NCT04646252
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The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular Events
Impaired Endothelial Glycocalyx Predicts Adverse Outcome in Subjects Without Overt Cardiovascular Disease: a 6 Year Follow up Study

Study Focus

Endothelial Dysfunction

Perfused Boundary Region of sublingual microvessels

Observational

other

Sponsor & Location

University of Athens

Athens, Greece

Timeline & Enrollment

N/A

Jan 10, 2013

Mar 28, 2023

500 participants

Primary Outcome

Major Adverse Cardiovascular events

Summary

We intend to recruit individuals who are referred for a routine screening in the primary
 prevention outpatient clinic of Attikon University hospital, Athens According to
 institutional protocols, a detailed medical history for atherosclerotic risk factors and
 current medication is recorded and a baseline clinical examination is performed. Moreover
 fasting blood samples are drawn to diagnose the presence of diabetes mellitus and
 hyperlipidemia. Glycocalyx examination is performed at the same visit. The subjects are
 revaluated at one month and then followed up according to the attending physician's
 instructions. All subjects are followed up for adverse events (death, stroke, myocardial
 infarction, hospitalization for heart failure) for 6 years after enrollment via telephonic
 contact and planned appointment at the outpatient clinic.

ICD-10 Classifications

Other peripheral vascular diseases
Atherosclerosis of arteries of extremities
Other specified peripheral vascular diseases
Renovascular hypertension
Other disorders of arteries and arterioles

Data Source

ClinicalTrials.gov

NCT04646252

Non-Device Trial