Endothelial Microparticles as Potential Biomarkers of Endothelial Dysfunction - Trial NCT04512404
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Study Focus
Sponsor & Location
Universiti Sains Malaysia
Timeline & Enrollment
N/A
Oct 13, 2016
Jan 31, 2021
Primary Outcome
EMP level and its correlation with endothelial function by pulse wave analysis,EMP level and its correlation with endothelial function by pulse wave analysis
Summary
Endothelial microparticles (EMP) have a promising role as a diagnostic and prognostic tool in
 the assessment of endothelial function. This study compares the levels of EMP in
 hypercholesterolaemia patients before and after treatment with statins and correlates it with
 the current method of assessing endothelial function using pulse wave analysis.
 
 The current available methods to assess endothelial function are tedious and not suitable to
 be applied clinically. Detecting EMP levels are simpler as it only involves routine blood
 taking which is better tolerated by patients.
 
 Outcome from this study will contribute to finding a potential diagnostic, prognostic and
 treatment assessment tool that is suitable to be used clinically. This will have a large
 impact in the management of cardiovascular-related disease that is prevalent worldwide and
 increasing in the developed countries.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT04512404
Non-Device Trial