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EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005 - Trial NCT04437368

Access comprehensive clinical trial information for NCT04437368 through Pure Global AI's free database. This Phase 2 trial is sponsored by Gyroscope Therapeutics Limited and is currently Recruiting. The study focuses on Dry Age-related Macular Degeneration. Target enrollment is 75 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT04437368
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov • NCT04437368
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EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
EXPLORE: A Phase II, Outcomes Assessor-masked, Multicentre, Randomised Study to Evaluate the Safety and Efficacy of Two Doses of GT005 Administered as a Single Subretinal Injection in Subjects With Geographic Atrophy Secondary to Age-related Macular Degeneration

Study Focus

GT005; Low Dose

Interventional

drug

Sponsor & Location

Gyroscope Therapeutics Limited

Palo Alto,Poway,Miami,Saint Petersburg,Indianapolis,West Des Moines,Baltimore,Boston,Reno,New York,Rochester,Cincinnati,Cleveland,Portland,Philadelphia,Memphis,Dallas,Morgantown,Melbourne E.,Marseille, Australia,France,Germany,Spain,United Kingdom,United States of America

Timeline & Enrollment

Phase 2

Jul 14, 2020

Feb 28, 2024

75 participants

Primary Outcome

Progression of geographic atrophy

Summary

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of
 GT005 administered as a single subretinal injection in subjects with geographic atrophy
 secondary to age-related macular degeneration (AMD).

ICD-10 Classifications

Peripheral retinal degeneration
Corneal degeneration
Hereditary retinal dystrophy
Optic atrophy in diseases classified elsewhere
Disorders of choroid and retina

Data Source

ClinicalTrials.gov

NCT04437368

Non-Device Trial