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The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts. - Trial NCT04400760

Access comprehensive clinical trial information for NCT04400760 through Pure Global AI's free database. This Phase 2/3 trial is sponsored by The University of The West Indies and is currently Recruiting. The study focuses on Platelet Dysfunction. Target enrollment is 25 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT04400760
Phase 2/3
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT04400760
View on ClinicalTrials.gov
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The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts.
The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts: The EDGE Study.

Study Focus

Platelet Dysfunction

DAPA Tx

Interventional

drug

Sponsor & Location

The University of The West Indies

Port Of Spain, Trinidad and Tobago

Timeline & Enrollment

Phase 2/3

May 01, 2020

Jun 30, 2022

25 participants

Primary Outcome

Platelet Reactions Units pre-DAPA Tx and post-DAPA Tx

Summary

Sodium GLucose Transport 2 inhibitors (SGLT2I), including dapagliflozin, reduce the
 likelihood of hospitalization for heart failure and death in persons with type 2 diabetes, of
 which the mechanism has not been fully elucidated. The mechanistic effects of dapagliflozin
 on platelet function profiles have not yet been ascertained. It remains unclear if this
 reduction in cardiovascular death is mediated by decreased platelet reactivity.

ICD-10 Classifications

Qualitative platelet defects
Antithrombotic drugs [platelet-aggregation inhibitors]
Essential (haemorrhagic) thrombocythaemia
Other thrombophilia
Haemorrhagic disorder due to circulating anticoagulants

Data Source

ClinicalTrials.gov

NCT04400760

Non-Device Trial