Hyperbaric VO2max Study - Trial NCT02356900
Access comprehensive clinical trial information for NCT02356900 through Pure Global AI's free database. This Phase 2 trial is sponsored by Duke University and is currently Terminated. The study focuses on Exercise Training. Target enrollment is 25 participants.
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Study Focus
Sponsor & Location
Duke University
Timeline & Enrollment
Phase 2
Feb 01, 2015
May 01, 2016
Primary Outcome
Change in Maximum Aerobic Capacity (VO2max) From Baseline to Post-training ( 72 Hours ),Change in Ventilatory Threshold (VT) From Baseline to Post-training (72 Hours),Mitochondrial Mass Change,Tfam Muscle Protein Content Change,Pgc-1a Coactivator Muscle Protein Content Change,COX-I Gene Expression Change,Muscle Phenotype Change
Summary
This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric
 environment for exercise performance at altitude. Subjects will complete a short,
 high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after
 this training phase, all subjects will be tested for maximum aerobic capacity at a simulated
 high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of
 mitochondrial oxidative capacity in a skeletal muscle biopsy.
 
 A group of individuals of similar characteristics completing this training program in a
 normoxic-normobaric environment will serve as a control.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT02356900
Non-Device Trial