Visit us at Medica, Dusseldorf, Germany 17-20 November 2025 at Hall 16, Stand D17-5 and ask us about our free AI tools and the document builder.
Pure Global

Top 100 Registration Holders 2022 in Brazil

Leading companies holding the most ANVISA medical device registrations registered in 2022, ranked by distinct registration numbers. Free market intelligence powered by Pure Global AI.

Top 100 - 2022

This comprehensive ranking showcases the top 100 medical device registration holders in Brazil's market for 2022, ranked by distinct ANVISA registration numbers. Registration holders are the companies legally responsible for medical devices in Brazil, often serving as distributors, importers, or local representatives for international manufacturers.

The top 100 holders collectively manage 2,693 registrations registered in 2022 out of 6,355 total ANVISA registrations (42.4% market coverage). The leading 10 holders alone account for 760 registrations (12.0%), demonstrating significant market concentration. Each entry displays distinct registration count, total product variations, unique technical categories, and their top 3 specialization categories to help you quickly understand what each company focuses on.

Understanding registration holder landscapes by year helps manufacturers identify potential distribution partners, assess competitive positioning, and evaluate market entry strategies for Brazil. Pure Global AI analyzes 100,000+ devices to deliver actionable partnership intelligence completely free.

Total Holders
1,261

Unique companies

Top 10 Share
12.0%

Market coverage

Top 100 Total
2,693

Registrations

Leader
#1

198 regs

DJ Fang

DJ Fang

MedTech Regulatory Expert

Need help with 30+ markets registration?

Pricing
Free consultation
Top 100 Registration Holders 2022
Leading companies holding the most ANVISA medical device registrations registered in 2022, ranked by distinct registration numbers.
RankRegistration HolderDistinct RegistrationsTotal ProductsTechnical CategoriesTop 3 CategoriesDetails
#1
VR MEDICAL IMPORTADORA E DISTRIBUIDORA DE PRODUTOS MÉDICOS LTDA198255116
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
Probes
Venous Catheter Kit
#2
MEDIX BRASIL LTDA10110128
FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES
Catheters
Probes
#3
MARDEN MEDICAL LTDA97978
Instrument Kit
Surgical Kit
Cannulas
#4
EMERGO BRAZIL IMPORT IMPORTACAO E DISTRIBUICAO DE PRODUTOS MEDICOS HOSPITALARES LTDA638940
Intraocular Lenses
PERIPHERAL ANGIOPLASTY BALLOON CATHETER
FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES
#5
MANDALA BRASIL IMPORTACAO E DISTRIBUICAO DE PRODUTO MEDICO HOSPITALAR LTDA555825
Catheters
Dilators
Infusion Sets
#6
PASSROD IMPORTAÇÃO E EXPORTAÇÃO DE PRODUTOS PARA SAÚDE LTDA - ME546040
Software
Body Fat Percentage Analyzer
Laser System For Therapy
#7
PHADIA DIAGNOSTICOS LTDA505343
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
ELECTROLYTES
GLUTAMIC PYRUVIC TRANSAMINASE (GPT OR ALT)
#8
JJGC INDÚSTRIA E COMÉRCIO DE MATERIAIS DENTÁRIOS S.A.49519
Dental Surgical Instruments
Dental Prosthesis Components
Dental Acrylic Resins
#9
ROCHE DIAGNÓSTICA BRASIL LTDA476729
Instrument for sample preparation and processing – pre-analytical phase
TROPONIN
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#10
SOL-MILLENNIUM BRASIL IMPORTACAO E EXPORTACAO LTDA46465
Disposable Syringes
Disposable Needles
Needle Adapter
#11
MULTILASER INDUSTRIAL S.A.454526
Limb Orthosis
Disposable Syringes
Disposable Needles
#12
BIOSUL PRODUTOS DIAGNOSTICOS LTDA - ME436428
GLYCATED HEMOGLOBIN (HbA1C)
DENGUE
Instrument for chromatography analysis
#13
BIOSYSTEMS NE COMÉRCIO DE PRODUTOS LABORATORIAIS E HOSPITALARES LTDA434325
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
CREATININE
URIC ACID
#14
RIOXI Ind., Com., Importação e Exportação de Equipamentos Hospitalares LTDA.414118
Nebulizer
Multifunctional Panel
Jet handpiece for cleaning medical devices
#15
SALLUS BRASIL PRODUTOS PARA SAUDE IMPORTACAO E EXPORTACAO LTDA414131
Instrument for hemostasis
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#16
AUTO SUTURE DO BRASIL LTDA.405624
Breathing Circuits
Surgical Burs
Trochars
#17
REACT TECHNOLOGY INDUSTRIA COMERCIO IMPORTACAO E EXPORTACAO DE PRODUTOS MEDICOS E HOSPITALARES LTDA393912
SINGLE ADMINISTRATION NERVE LOCATOR ANESTHESIA KIT
Metal Cannulas
Surgical Burs
#18
GMRB COMÉRCIO DE PRODUTOS MÉDICOS E DIAGNÓSTICOS LTDA356617
CHLAMYDIA
HERPES VIRUS (HHV 2)
MYCOPLASMA
#19
SDI HOLDINGS PTY LTD DO BRASIL344517
Light-Cured Composite Resin
Dental Whitening Agents
Glass Ionomer Cement
#20
SIEMENS HEALTHCARE DIAGNÓSTICOS LTDA343925
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
Instrument for nucleic acid analysis
#21
Enzytec Biotecnologia Ltda.334519
Instrument for nucleic acid analysis
STREPTOCOCCUS
Instrument for cell and platelet analysis or counting
#22
ATS PRODUTOS MEDICO - CIRURGICOS LTDA323213
Instrumentation for Laparoscopy
Catheters
Endoscopic Instruments
#23
ENDOBRAX COMERCIO, IMPORTAÇÃO E EXPORTAÇÃO DE EQUIPAMENTOS MEDICOS LTDA32325
Disposable Syringes
Infusion Sets
Varicose Vein Ligation Kit
#24
VIGODENT INDUSTRIA E COMERCIO LTDA.323216
Dental Files
Finishing and Polishing Material
Dental Whitening Agents
#25
OSSTEM IMPLANT BRASIL LTDA30318
Surgical Instrument For Dental Implants
Dental Implant Components
Impression Coping
#26
FIRSTLAB INDUSTRIA IMPORTACAO E EXPORTACAO DE PRODUTOS PARA LABORATORIOS LTDA293115
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
Instrument for analysis of general biochemistry, hormones, drugs or proteins
C-REACTIVE PROTEIN
#27
CARDIO MEDICAL INDUSTRIAL LTDA28328
Tube For Extracorporeal Circulation
CARDIOPULMONARY BYPASS SYSTEM AND ASSOCIATED DEVICES
Invasive vascular ultrasound system probe
#28
SALUTZ INDUSTRIA E COMERCIO DE PRODUTOS PARA SAUDE LTDA28285
Dental Burs
Limb Orthosis
Surgical instruments
#29
MEDSTAR IMPORTAÇÃO E EXPORTAÇÃO LTDA272919
Kit For Vitrectomy
Sterilizer
Video Camera for Endoscopy
#30
SEBIA IMPORTAÇÕES COMERCIALIZAÇÃO E DISTRIBUIÇÃO DE APARELHOS E REATIVOS PARA DIAGNÓSTICO IN VITRO LTDA.275010
CHLAMYDIA
HERPES VIRUS (HHV 2)
HERPES VIRUS (HHV 3) - VARICELLA ZOSTER
#31
FX MATERIAIS MEDICOS HOSPITALARES LTDA26267
Infusion Sets
Disposable Scalpel Blades
Collection Bags
#32
JOHNSON & JOHNSON DO BRASIL INDÚSTRIA E COMÉRCIO DE PRODUTOS PARA SAÚDE LTDA25348
Contact Lenses
Instrumental For Orthopedic Implant
ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
#33
QUIBASA - QUIMICA BASICA LTDA252525
25 HYDROXYVITAMIN D3 OF VITAMIN D
ANTISTREPTOLYSIN
ANTIBODY FOR MULTIPLE HUMAN T-LYMPHOTROPIC VIRUSES (HTLV)
#34
DIAGNÓSTICA INDÚSTRIA E COMÉRCIO LTDA - ME244020
DENGUE
COMBINED PARAMETERS - RESPIRATORY PANEL
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS III
#35
E TAMUSSINO E CIA LTDA242513
Surgical instruments
Probes
Gastrostomy Kit
#36
LABORATORIOS B. BRAUN S/A243311
Hemodialysis Set
Infusion Sets
Disposable Syringes
#37
CEDRS - GESTAO EMPRESARIAL LTDA232314
SURGICAL FACE MASK
Disposable Gloves
Hospital Apparel
#38
CIRURGICA FERNANDES - COMERCIO DE MATERIAIS CIRURGICOS E HOSPITALARES - SOCIEDADE LIMITADA232415
Surgical instruments
Masks
Probes
#39
MED FLEX INDÚSTRIA E COMÉRCIO DE EQUIPAMENTOS MÉDICOS LTDA232312
Breathing Circuits
Surgical Apparel
Cannulas
#40
BIO BRASIL BIOTECNOLOGIA LTDA223011
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
CORONAVIRUS
ROTAVIRUS
#41
LATIN HEALTH IMPORTADORA E DISTRIBUIDORA LTDA.222214
Introducers
PERIPHERAL ANGIOPLASTY BALLOON CATHETER
Disposable Syringes
#42
NL COMÉRCIO EXTERIOR LTDA222313
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
ANTIPHOSPHOLIPID ANTIBODY
INSTRUMENT FOR GLUCOSE AND LIPID PROFILE – POINT OF CARE TESTING (PROFESSIONAL)
#43
Vida Biotecnologia Ltda - ME222217
Instrument for blood gas, ion or pH analysis
LYSIS SOLUTION
Instrument for urine analysis
#44
ABBOTT LABORATORIOS DO BRASIL LTDA213012
HERPES VIRUS (HHV 1)
HERPES VIRUS (HHV 2)
IRON
#45
ALPHALIFE MATERIAIS MÉDICO HOSPITALARES LTDA.21216
Nasal Shaper
Disposable Blades
Buffer
#46
DCB DISTRIBUIDORA CIRURGICA BRASILEIRA LTDA212110
Catheters
Tracheal Tube
Disposable Gloves
#47
MEDMAX COMÉRCIO DE EQUIPAMENTOS MÉDICOS E SIMILARES LTDA ME212119
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
ALBUMIN
CORONAVIRUS
#48
MR SAUDE LTDA212210
Lancets
Collection Bags
Disposable Needles
#49
GOLD ANALISA DIAGNOSTICA LTDA202018
Instrument intended for immunoassays
TREPONEMA PALLIDUM
D-DIMER
#50
Humanna Medical Ltda20208
Surgical Kit
Disposable Blades
Surgical instruments
#51
MICROPORT SCIENTIFIC VASCULAR BRASIL LTDA203117
CATHETER FOR RADIOFREQUENCY CARDIAC ABLATION SYSTEM
Single-use cardiac electrophysiology catheter
Calculus Extractor
#52
R3A MEDICAL INDUSTRIA E COMERCIO DE PRODUTOS HOSPITALARES LTDA20204
Surgical Kit
Cannulas
Instrument Kit
#53
STRYKER DO BRASIL LTDA202513
Instrumental For Orthopedic Implant
Surgical instruments
Bone Drilling Burs
#54
STUHR COMERCIAL IMPORTADORA E EXPORTADORA LTDA202011
Articulated Forceps
Surgical instruments
Needles
#55
AGROMASS BRASIL AGROPECUARIA - IMPORTACAO E EXPORTACAO LTDA191911
Tracheal Tube
Catheters
Needle Adapter
#56
MEDSALUS INDUSTRIA E COMERCIO DE PRODUTOS DE USO UNICO LTDA19195
Surgical Kit
Hospital Apparel
Surgical Drape
#57
Nanosens Ltda19198
ALBUMIN
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
ALPHA 1-MICROGLOBULIN
#58
BIOSYS LTDA182213
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
ANTI-INFLIXIMAB (IFX) ANTIBODIES
COMBINED PARAMETERS - RESPIRATORY PANEL
#59
CONMED DO BRASIL COMERCIO, IMPORTACAO E EXPORTACAO DE PRODUTOS MEDICOS HOSPITALARES LTDA183213
CABLE/ELECTRODE FOR ELECTROCARDIOGRAPH
Electrosurgical handpiece/electrode for open surgery, monopolar, reusable
Handpiece/Endoscopic electrosurgical electrode, monopolar, single use
#60
DR IMPORTAÇÃO, EXPORTAÇÃO E DISTRIBUIÇÃO LTDA182312
Electric Motor
ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
Ureteral Stent
#61
EXCELMED DISTRIBUIDORA DE MATERIAIS MEDICOS E ODONTOLOGICOS LTDA18189
Disposable Gloves
Disposable Syringes
Catheters
#62
TOTAL MEDICAL BRASIL INDUSTRIA E COMERCIO DE PRODUTOS MEDICO-HOSPITALARES LTDA18186
Probes
Catheters
Cannulas
#63
BIOBLASTI INDUSTRIA COMERCIO IMPORTACAO E EXPORTACAO DE BIOMATERIAIS E PRODUTOS BIOTECNOLOGICOS LTDA - EPP17175
Surgical Kit
Instrument Kit
SINGLE ADMINISTRATION NERVE LOCATOR ANESTHESIA KIT
#64
BRAVI INDUSTRIA E COMERCIO DE PRODUTOS ODONTOLOGICOS S.A.17176
Dental Whitening Agents
Acid Conditioners
Pastes For Prophylaxis and Dental Polishing
#65
HORIBA INSTRUMENTS BRASIL LTDA173217
GLUCOSE
CREATININE
GAMMA-GLUTAMYL TRANSPEPTIDASE (GGT)
#66
MEDLEVENSOHN COMÉRCIO E REPRESENTAÇÕES DE PRODUTOS HOSPITALARES LTDA172413
URINE TEST STRIP
Disposable Needles
Catheters
#67
MINDRAY DO BRASIL COMÉRCIO E DISTRIBUIÇÃO DE EQUIPAMENTOS MÉDICOS LTDA.172112
Collection Bags
Instrument for cell and platelet analysis or counting
Pressure and Volume Ventilator
#68
VYTTRA DIAGNOSTICOS S.A.172014
SELF-TEST FOR SARS-COV-2 ANTIGEN (CORONAVIRUS)
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
CORONAVIRUS
#69
BIOTECH LOGISTICA LTDA16163
Disposable Syringes
Disposable Gloves
Disposable Needles
#70
DRAGER INDUSTRIA E COMERCIO LTDA16184
Filter for Mechanical Ventilation
Equipment Stand
Neonatal Incubator
#71
Eco Diagnostica Ltda162114
SELF-TEST FOR SARS-COV-2 ANTIGEN (CORONAVIRUS)
SELF-TEST FOR GLUCOSE
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
#72
Lismed Comércio Importação e Exportação Ltda16165
Surgical instruments
Dressing
Bags (Water, Silicone, Gel, Ice and Others)
#73
NAYR INDUSTRIA, COMERCIO E DISTRIBUICAO DE PRODUTOS LTDA161610
Tracheal Tube
Surgical Drape
Probes
#74
NEVE INDUSTRIA E COMERCIO DE PRODUTOS CIRURGICOS LTDA.16163
Gauze Sponges
Protectors
Disposable Gloves
#75
ORBITAE DIAGNOSTICOS LTDA162613
SELF-TEST FOR SARS-COV-2 ANTIGEN (CORONAVIRUS)
HELICOBACTER PYLORI
INFLUENZA VIRUS A and B
#76
ARGOSLAB DISTRIBUIDORA DE PRODUTOS PARA LABORATÓRIOS LTDA151812
CORONAVIRUS
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
NITRITE
#77
BECKMAN COULTER DO BRASIL COMÉRCIO E IMPORTAÇÃO DE PRODUTOS DE LABORATÓRIO LTDA151811
Instrument for sample preparation and processing – pre-analytical phase
Instrument for urine analysis
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#78
BIOMED EQUIPAMENTOS DE BIOMEDIDAS LTDA15157
Electrodes
SUBCUTANEOUS NEEDLE ELECTRODE
ANALYTICAL CUTANEOUS ELECTRODE
#79
BIOMOLECULAR TECHNOLOGY COMÉRCIO, IMPORTAÇÃO, EXPORTAÇÃO E DISTRIBUIÇÃO DE MATERIAIS MÉDICOS E LABORATORIAIS LTDA - EPP152012
Software
Self-test instrument for glucose
SELF-TEST FOR GLUCOSE
#80
BIOTEC BIOLOGICA INDÚSTRIA FARMACÊUTICA LTDA.15158
Hospital Apparel
Catheters
Masks
#81
JOHNSON & JOHNSON DO BRASIL INDÚSTRIA E COMÉRCIO DE PRODUTOS PARA SAÚDE LTDA15193
Suture Thread
Surgical Sutures and Tapes
Surgical Hemostatics
#82
MAXSTER INDÚSTRIA E COMÉRCIO LTDA15156
Surgical Drape
Sterile Disposable Drape
Surgical Apparel
#83
O-LINKE MEDICAL LTDA.15158
INTERNAL VERTEBRAL COLUMN FIXATION SYSTEMS
Surgical instruments
Disposable Blades
#84
ONE IMPLANTES LTDA15246
Surgical instruments
ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
Non-Absorbable Special Plate for Osteosynthesis
#85
CITYMEDIC INDUSTRIA, COMERCIO E SERVICOS DE MATERIAIS HOSPITALARES - LTDA - ME14148
Collection Vials
Probes
SURGICAL FACE MASK
#86
Domo Salute Consultoria Regulatória Ltda141513
Dental Files
SELF-TEST FOR SARS-COV-2 ANTIGEN (CORONAVIRUS)
Air Mixer
#87
INTEGRA LIFESCIENCES BRAZIL LTDA14156
Surgical instruments
Instrument Kit
Surgical Retractor/Approximator
#88
SIRONA DENTAL COMÉRCIO DE PRODUTOS E SISTEMAS ODONTOLÓGICOS LTDA.141710
Dental Absorbent Paper Points
Dental Porcelain/Ceramic
Gutta-Percha
#89
Smith & Nephew Comércio de Produtos Médicos Ltda.14249
ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
NON-BIOABSORBABLE, STERILE ORTHOPEDIC BONE SCREW
Surgical instruments
#90
programa nacional de controle de qualidade ltda14149
COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
C-REACTIVE PROTEIN
ANTIBODY FOR MULTIPLE HUMAN T-LYMPHOTROPIC VIRUSES (HTLV)
#91
BARD BRASIL INDÚSTRIA E COMÉRCIO DE PRODUTOS PARA A SAÚDE LTDA.131611
PERIPHERAL ANGIOPLASTY BALLOON CATHETER
Breast Biopsy Equipment
CATHETER LOCATION SYSTEM
#92
BECTON DICKINSON INDÚSTRIAS CIRÚRGICAS LTDA.13158
FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES
SOLUTION FOR PERFORMANCE EVALUATION OF EQUIPMENT COMPONENTS
CULTURE MEDIA AND DEVICES FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING
#93
BL INDÚSTRIA OTICA LTDA13144
Surgical instruments
Disposable Surgical Forceps
Microsurgery Scissors
#94
CML- Centro Médico Logístico Ltda13169
Intraocular Lenses
Ultrasound device for ophthalmology
Surgical Scalpel
#95
HRA industria comercio importação e exportação de produtos medicos hospitalares ltda13137
BIOPSY NEEDLE
SINGLE ADMINISTRATION NERVE LOCATOR ANESTHESIA KIT
Skull Fixator
#96
IN VITRO DIAGNOSTICA LTDA131312
GLYCATED HEMOGLOBIN (HbA1C)
THYROXINE (T4)
TRIIODOTHYRONINE (T3)
#97
LANG ELETRO MEDICINA LTDA - EPP13137
Surgical Kit
Bipolar Forceps
ELECTROSURGICAL CABLE/ELECTRODE (Power less than or equal to 50W)
#98
MASSAR PROTEÇÃO E HIGIENE LTDA13134
Surgical Kit
SURGICAL APPAREL SET, SURGICAL DRAPE
Bandages
#99
MICO BIOMED DO BRASIL LTDA13178
BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
COMBINED PARAMETERS - RESPIRATORY PANEL
CORONAVIRUS
#100
PROAMED COMERCIO ATACADISTA DE PRODUTOS PARA SAUDE E CORRELATOS LTDA13137
Needle Holder
Forceps
Bipolar Forceps

Looking for Distribution Partners in Brazil?

Use these rankings to identify potential registration holders for your products. Our experts can help you evaluate partners and navigate ANVISA registration requirements.