Top 100 Registration Holders in Brazil

Leading companies holding the most ANVISA medical device registrations, ranked by distinct registration numbers. Free market intelligence powered by Pure Global AI.

Top 100 Rankings

This comprehensive ranking showcases the top 100 medical device registration holders in Brazil's market, ranked by distinct ANVISA registration numbers. Registration holders are the companies legally responsible for medical devices in Brazil, often serving as distributors, importers, or local representatives for international manufacturers.

The top 100 holders collectively manage 32,317 registrations out of 94,995 total ANVISA registrations (34.0% market coverage). The leading 10 holders alone account for 10,186 registrations (10.7%), demonstrating significant market concentration. Each entry displays distinct registration count, total product variations, unique technical categories, and their top 3 specialization categories to help you quickly understand what each company focuses on.

Understanding registration holder landscapes helps manufacturers identify potential distribution partners, assess competitive positioning, and evaluate market entry strategies for Brazil. Pure Global AI analyzes 100,000+ devices to deliver actionable partnership intelligence completely free.

Total Holders

4,102

Unique companies

Top 10 Share

10.7%

Market coverage

Top 100 Total

32,317

Registrations

Leader

2,430 regs

DJ Fang

MedTech Regulatory Expert

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Top 100 Registration Holders

Leading companies holding the most ANVISA medical device registrations, ranked by distinct registration numbers.

Rank	Registration Holder	Distinct Registrations	Total Products	Technical Categories	Top 3 Categories
#1	VR MEDICAL IMPORTADORA E DISTRIBUIDORA DE PRODUTOS MÉDICOS LTDA	2,430	3,284	654	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Catheters Surgical Kit
#2	SIEMENS HEALTHCARE DIAGNÓSTICOS LTDA	1,379	1,690	292	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II SOFTWARE FOR MEDICAL IMAGE PROCESSING
#3	ROCHE DIAGNÓSTICA BRASIL LTDA	1,169	1,547	293	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS III
#4	AUTO SUTURE DO BRASIL LTDA.	981	1,574	238	Catheters Cannulas Instrumental for Spine Implant
#5	ABBOTT LABORATORIOS DO BRASIL LTDA	878	1,196	233	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS HERPES VIRUS (HHV 4) - EPSTEIN-BARR VIRUS (EBV)
#6	EMERGO BRAZIL IMPORT IMPORTACAO E DISTRIBUICAO DE PRODUTOS MEDICOS HOSPITALARES LTDA	749	1,011	291	Catheters Software Masks
#7	PASSROD IMPORTAÇÃO E EXPORTAÇÃO DE PRODUTOS PARA SAÚDE LTDA - ME	669	787	261	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Surgical instruments Trochars
#8	STRYKER DO BRASIL LTDA	660	1,007	150	Instrumental For Orthopedic Implant Instrument Kit ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
#9	CIRURGICA FERNANDES - COMERCIO DE MATERIAIS CIRURGICOS E HOSPITALARES - SOCIEDADE LIMITADA	638	712	112	Probes Cannulas Catheters
#10	VYTTRA DIAGNOSTICOS S.A.	633	642	169	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II ANTIBODY ANTI-EXTRACTABLE NUCLEAR ANTIGENS (ENA)
#11	ARGOSLAB DISTRIBUIDORA DE PRODUTOS PARA LABORATÓRIOS LTDA	619	666	243	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II ANTIBODY FOR CELIAC DISEASE FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES
#12	JOHNSON & JOHNSON DO BRASIL INDÚSTRIA E COMÉRCIO DE PRODUTOS PARA SAÚDE LTDA	598	1,247	126	Instrument Kit ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES Surgical instruments
#13	LABORATORIOS B. BRAUN S/A	518	695	126	Surgical instruments Infusion Sets Instrument Kit
#14	BECKMAN COULTER DO BRASIL COMÉRCIO E IMPORTAÇÃO DE PRODUTOS DE LABORATÓRIO LTDA	496	597	156	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II SOLUTION FOR PERFORMANCE EVALUATION OF EQUIPMENT COMPONENTS
#15	JJGC INDÚSTRIA E COMÉRCIO DE MATERIAIS DENTÁRIOS S.A.	477	541	45	Dental Prosthesis Components Dental Instruments Dental Surgical Instruments
#16	QR CONSULTING, IMPORTACAO E DISTRIBUICAO DE PRODUTOS MEDICOS LTDA	421	549	131	CORONAVIRUS DRUGS OF ABUSE PANEL Cannulas
#17	BOSTON SCIENTIFIC DO BRASIL LTDA	415	724	123	Catheters URINARY STENT PERIPHERAL ANGIOPLASTY BALLOON CATHETER
#18	MEDSTAR IMPORTAÇÃO E EXPORTAÇÃO LTDA	394	504	143	Instrument Kit Masks Instrument for sample preparation and processing – pre-analytical phase
#19	MANDALA BRASIL IMPORTACAO E DISTRIBUICAO DE PRODUTO MEDICO HOSPITALAR LTDA	373	483	145	Solution for Intradermal Filling Catheters Intraocular Lenses
#20	MARDEN MEDICAL LTDA	362	362	32	Surgical Kit Instrument Kit Cannulas
#21	Smith & Nephew Comércio de Produtos Médicos Ltda.	355	527	72	Surgical instruments Dressing Instrumental For Orthopedic Implant
#22	ZIMMER BIOMET BRASIL LTDA	343	629	73	Instrument Kit Instrumental For Orthopedic Implant Surgical instruments
#23	MEDIX BRASIL LTDA	342	352	49	Disposable Gloves FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES Surgical Apparel
#24	PHADIA DIAGNOSTICOS LTDA	331	376	155	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS IMMUNOGLOBULIN E
#25	MINDRAY DO BRASIL COMÉRCIO E DISTRIBUIÇÃO DE EQUIPAMENTOS MÉDICOS LTDA.	330	417	126	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Instrumental For Orthopedic Implant LYSIS SOLUTION
#26	E-MED PRODUTOS MÉDICO-HOSPITALARES LTDA - ME	326	326	68	Instrument Kit Catheters Endoscopic Instruments
#27	WINNER INDUSTRIA DE DESCARTAVEIS LTDA	325	326	37	Surgical Drape SURGICAL GOWN SET, SURGICAL DRAPE AND GAUZE SPONGE Surgical Apparel
#28	BIOSYS LTDA	315	378	125	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS III Instrument for analysis of general biochemistry, hormones, drugs or proteins
#29	ORTHO CLINICAL DIAGNÓSTICS DO BRASIL PRODUTOS PARA SAÚDE LTDA	311	402	145	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Instrument for analysis of general biochemistry, hormones, drugs or proteins
#30	EUROIMMUN BRASIL MEDICINA DIAGNOSTICA LTDA	308	414	114	ANTINUCLEAR ANTIBODY (ANA) BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS ANTIBODY FOR CELIAC DISEASE
#31	BIOMÉDICA EQUIPAMENTOS E SUPRIMENTOS HOSPITALARES LTDA	304	365	75	Instrumental for Spine Implant Surgical instruments Cannulas
#32	WERFEN MEDICAL LTDA	301	330	65	ANTINUCLEAR ANTIBODY (ANA) COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II ANTIBODY FOR CELIAC DISEASE
#33	LABTEST DIAGNOSTICA S/A	296	296	135	Instrument for analysis of general biochemistry, hormones, drugs or proteins BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
#34	QUIBASA - QUIMICA BASICA LTDA	294	294	110	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II CORONAVIRUS BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#35	IN VITRO DIAGNOSTICA LTDA	291	299	110	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II GLYCATED HEMOGLOBIN (HbA1C)
#36	CEI COMÉRCIO EXPORTAÇÃO E IMPORTAÇÃO DE MATERIAIS MÉDICOS LTDA	290	346	80	Surgical Kit Catheters Laboratory/Hospital Refrigerator or Freezer
#37	BECTON DICKINSON INDÚSTRIAS CIRÚRGICAS LTDA.	288	337	77	FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Disposable Syringes
#38	Enzytec Biotecnologia Ltda.	264	321	100	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Instrument for cell and platelet analysis or counting LYSIS SOLUTION
#39	CEDRS - GESTAO EMPRESARIAL LTDA	263	267	48	Surgical Kit Masks Connectors
#40	ARTHREX DO BRASIL IMPORTACAO E COMERCIO DE EQUIPAMENTOS MÉDICOS LTDA	262	344	61	Instrument Kit Surgical instruments ANCHOR
#41	DESCARPACK DESCARTAVEIS DO BRASIL LTDA	257	279	55	Disposable Gloves Surgical Apparel Infusion Sets
#42	LABORLAB PRODUTOS PARA LABORATÓRIOS LTDA EPP	248	357	140	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS LYSIS SOLUTION
#43	CIENLABOR INDUSTRIA E COMERCIO LTDA	244	258	75	Instrument Kit External Fixators Trochars
#44	BIO-RAD LABORATORIOS BRASIL LTDA	244	350	75	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS III COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS IV
#45	CPMH - Comércio e Indústria de Produtos Médico-Hospitalares e Odontológicos LTDA.	241	252	31	External Fixators Instrumental For Orthopedic Implant Surgical instruments
#46	CRAL ARTIGOS PARA LABORATORIO LTDA	240	240	23	FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES Dressing Lancets
#47	DIASORIN LTDA	239	343	109	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Instrument intended for immunoassays HERPES VIRUS (HHV 4) - EPSTEIN-BARR VIRUS (EBV)
#48	ST. JUDE MEDICAL BRASIL LTDA.	236	452	75	Catheters Introducers Heart Valve Sizer
#49	E TAMUSSINO E CIA LTDA	234	358	72	Surgical instruments Catheters Biopsy Device
#50	NUTRIEX IMPORTACAO E EXPORTACAO DE PRODUTOS NUTRICIONAIS E FARMOQUIMICOS LTDA	231	260	46	Disposable Syringes Surgical Apparel Solution for Intradermal Filling
#51	Vida Biotecnologia Ltda - ME	231	232	86	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II GLYCATED HEMOGLOBIN (HbA1C) BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#52	COLOPLAST DO BRASIL LTDA.	229	287	47	Collection Bags Catheters Dressing
#53	3M DO BRASIL LTDA	226	518	51	Dressing Limb Orthosis Light-Cured Composite Resin
#54	Eco Diagnostica Ltda	224	243	109	CORONAVIRUS DENGUE COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
#55	RAZEK EQUIPAMENTOS LTDA	223	223	49	Surgical Kit Surgical instruments Surgical Burs
#56	BIOMOLECULAR TECHNOLOGY COMÉRCIO, IMPORTAÇÃO, EXPORTAÇÃO E DISTRIBUIÇÃO DE MATERIAIS MÉDICOS E LABORATORIAIS LTDA - EPP	222	266	92	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS SELF-TEST FOR GLUCOSE CORONAVIRUS
#57	LABOR IMPORT COMERCIAL IMPORTADORA E EXPORTADORA LTDA	217	228	44	FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES Scalp Vein Sets Disposable Needles
#58	BIODINAMICA QUIMICA E FARMACEUTICA LTDA	216	216	70	Light-Cured Composite Resin Material for Root Canal Disinfection and Obturation Dental Adhesive
#59	Diagmaster Científica ltda	210	232	86	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS BILIRUBIN COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
#60	KOLPLAST CI LTDA	209	209	52	FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES Colpocitology Kit Disposable Speculum
#61	HTS - TECNOLOGIA EM SAÚDE, COMÉRCIO, IMPORTAÇÃO E EXPORTAÇÃO LTDA	209	223	42	Cannulas Catheters Introducers
#62	BARD BRASIL INDÚSTRIA E COMÉRCIO DE PRODUTOS PARA A SAÚDE LTDA.	209	332	46	Venous Catheter Kit Catheter with Infusion Port Catheters
#63	CREMER S/A	197	200	47	Adhesive Tapes and Bandages Dressing Gauze Sponges
#64	DIAGNÓSTICA INDÚSTRIA E COMÉRCIO LTDA - ME	194	239	78	CORONAVIRUS FLASK OR MATERIAL FOR COLLECTION, STORAGE OR TRANSPORT OF BIOLOGICAL SAMPLES Instrument for sample preparation and processing – pre-analytical phase
#65	Humanna Medical Ltda	191	191	36	Surgical Kit Cannulas Disposable Blades
#66	DENTSPLY IND.COM. LTDA	189	231	47	Dental Implant Components Dental Porcelain/Ceramic Surgical Kit
#67	Domo Salute Consultoria Regulatória Ltda	185	233	84	Software SOFTWARE FOR MEDICAL IMAGE PROCESSING SURGICAL STAPLER
#68	BIOSYSTEMS NE COMÉRCIO DE PRODUTOS LABORATORIAIS E HOSPITALARES LTDA	183	193	75	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BILIRUBIN TOTAL PROTEIN
#69	JOÃOMED COMÉRCIO DE MATERIAIS CIRÚRGICOS S/A	182	185	53	Cannulas Infusion Sets Collection Bags
#70	SOL-MILLENNIUM BRASIL IMPORTACAO E EXPORTACAO LTDA	182	183	21	Disposable Syringes Disposable Needles Scalp Vein Sets
#71	BL INDÚSTRIA OTICA LTDA	181	245	34	Surgical instruments Contact Lenses Solution For Ophthalmic Use
#72	KHAYROS DIAGNOSTICA FABRICACAO, COMERCIALIZACAO E DISTRIBUICAO DE PRODUTOS LTDA	178	179	97	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS III COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II IMMUNOGLOBULIN E
#73	MERIT MEDICAL COMERCIALIZAÇÃO, DISTRIBUIÇÃO, IMPORTAÇÃO E EXPORTAÇÃO DE PRODUTOS HOSPITALARES LTDA	176	212	49	Catheters CATHETER INTRODUCER KIT / CATHETERIZATION SUPPORT KIT Catheter Introducer System
#74	BMR MEDICAL S.A.	175	177	41	Infusion Sets Venous Catheter Kit Dressing
#75	RICHARD WOLF BRASIL EQUIPAMENTOS MEDICINAIS LTDA	174	201	52	Surgical instruments Tubes Trochars
#76	GOLD ANALISA DIAGNOSTICA LTDA	172	172	87	CORONAVIRUS DENGUE GLYCATED HEMOGLOBIN (HbA1C)
#77	LINE LIFE CARDIOVASCULAR COM DE PROD MED E HOSP LTDA	172	184	42	Biopsy Device Introducers Catheters
#78	KATAL BIOTECNOLOGICA INDUSTRIA E COMERCIO LTDA	167	167	77	LYSIS SOLUTION COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#79	RANDOX BRASIL LTDA	167	170	74	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS BILIRUBIN
#80	H STRATTNER E CIA LTDA	165	177	85	Surgical instruments Trochars Endoscopic Instruments
#81	ICU MEDICAL DO BRASIL PRODUTOS HOSPITALARES LTDA	163	226	56	Cannulas Tracheostomy Kit Probes
#82	HORIBA INSTRUMENTS BRASIL LTDA	163	218	57	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS Instrument for hemostasis
#83	KOVALENT DO BRASIL LTDA	162	170	76	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II C-REACTIVE PROTEIN Instrument for blood gas, ion or pH analysis
#84	LABINBRAZ COMERCIAL LTDA	160	174	74	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II Instrument for analysis of general biochemistry, hormones, drugs or proteins BILIRUBIN
#85	WAMA PRODUTOS PARA LABORATORIO LTDA	158	158	78	URINE TEST STRIP Instrument for urine analysis COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II
#86	GE HEALTHCARE DO BRASIL COMERCIO E SERVICOS PARA EQUIPAMENTOS MEDICO-HOSPITALARES LTDA	157	223	43	Software Ultrasound Device Magnetic Resonance Imaging Equipment
#87	GM DOS REIS INDUSTRIA E COMERCIO LTDA	157	157	42	Instrumental For Orthopedic Implant ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES NON-BIOABSORBABLE, NON-STERILE ORTHOPEDIC BONE SCREW
#88	PROMEDON DO BRASIL PRODUTOS MEDICO HOSPITALARES LTDA	156	246	67	Dressing Urethral Prostheses Catheters
#89	ORTOCIR ORTOPEDIA CIRURGIA LTDA	155	232	49	Instrumental For Orthopedic Implant Instrument Kit ORTHOPEDIC FIXATION SYSTEMS AND ASSOCIATED DEVICES
#90	MEDIVAX INDÚSTRIA E COMÉRCIO LTDA	149	226	52	CHLAMYDIA ANTICYTOPLASMIC ANTIBODY BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS
#91	Autentica Medical Importação Comercio e Serviços LTDA-ME	148	211	58	Instrumental For Orthopedic Implant Surgical instruments INTERNAL VERTEBRAL COLUMN FIXATION SYSTEMS
#92	INJEX INDÚSTRIAS CIRÚRGICAS LTDA	148	155	36	Disposable Syringes Disposable Needles Surgical Apparel
#93	VIGODENT INDUSTRIA E COMERCIO LTDA.	148	148	36	Light-Cured Composite Resin Dental Impression Material Dental Files
#94	POLAR FIX INDUSTRIA E COMERCIO DE PRODUTOS HOSPITALARES LTDA	147	160	26	Surgical Kit Gauze Sponges Dressing
#95	PRODIGY COMPANY LTDA	147	148	22	Needles TATTOO/PERMANENT MAKEUP MACHINE Needle Adapter
#96	PHAREBEE DIAGNOSTICOS COMERCIO IMPORTACAO E EXPORTACAO DE PRODUTOS LTDA	147	165	72	BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS RESPIRATORY SYNCYTIAL VIRUS (RSV) CANDIDA SP
#97	MONTSERRAT COMERCIAL IMPORTADORA E EXPORTADORA LTDA	147	147	44	Surgical instruments Elastic Compression Stockings Masks
#98	BHIO SUPPLY INDUSTRIA E COMERCIO DE EQUIPAMENTOS MEDICOS S/A	146	148	49	Surgical instruments Cannulas Trochars
#99	ABBOTT DIAGNOSTICOS RAPIDOS S.A.	146	201	58	DRUGS OF ABUSE PANEL COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II Lancets
#100	BIOTECNICA INDUSTRIA E COMERCIO LTDA	146	149	80	COMBINED PARAMETERS IN THE SAME PRODUCT - CLASS II BUFFERS, DILUENTS AND OTHER SOLUTIONS FOR LABORATORY ANALYSIS GLYCATED HEMOGLOBIN (HbA1C)

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