Magnesium sulphate versus dexmedetomidine for cough suppression during anesthetic emergence in smokers: A randomized double _ blind controlled trial - Trial PACTR202308591985746
Access comprehensive clinical trial information for PACTR202308591985746 through Pure Global AI's free database. This Phase 4 trial is sponsored by faculty of medicine ain shams university and is currently Recruiting. The study focuses on Anaesthesia.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to Pan Africa Clinical Trials Registry data, helping medical device and pharmaceutical companies navigate clinical research efficiently.
Study Focus
Sponsor & Location
faculty of medicine ain shams university
no
Timeline & Enrollment
Phase 4
Jul 20, 2022
Sep 07, 2023
Summary
Cough during the perioperative period is usually transient and self-limiting. On emergence from anesthesia, cough may protect against aspiration. However, cough can also result in perioperative morbidity, including tachyarrhythmia, arterial hypertension, cardiovascular collapse, and airway complications, and it may increase intracranial, intra abdominal, and intraocular pressure .Cigarette smokers known to have respiratory problems during induction of anesthesia with increased incidence of laryngospasm and cough during extubation as the integrity of epithelium lost by smoke irritation.Multiple medications have been shown to reduce emergence coughing, such as lidocaine (i.v., intracuff, topical, and tracheal routes), dexmedetomidine, fentanyl, and remifentanil.The aim of this study is to investigate and compare the effect of dexmedetomidine and magnesium sulphate on the prevention of emergence cough after general anesthesia in smokers performing lower abdominal surgeries.
ICD-10 Classifications
Data Source
Pan Africa Clinical Trials Registry
PACTR202308591985746
Non-Device Trial