Effectiveness of Preoperative Vaginal Cleansing with Povidone-Iodine in Post-ceasarean Infectious Morbidity; A Randomized Controlled Trial. - Trial PACTR201709002597110

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Summary

Background: Globally, caesarean section is the commonest major surgical procedure performed by obstetricians. However caesarean section is associated with infectious morbidity. Pre-operative vaginal cleansing with povidone-iodine may reduce the infectious morbidity.Aim: To determine the effectiveness of preoperative vaginal cleansing with povidone-iodine in reducing post-caesarean maternal infectious morbidities.Methodology: This will be a randomized controlled trial in which consented pregnant women booked for caesarean section will be randomized into 2 groups. Group 1 women will receive preoperative vaginal cleansing with povidone-iodine prior to caesarean section while group 2 women will not. After caesarean section , there will be daily check of clinical parameters of the 2 groups of women such as temperature, abdominal tenderness, rate of uterine involution and foul smelling vaginal discharge. Urine microscopy, culture and sensitivity and malarial parasitaema will be done on the participants who have fever to rule out urinary tract infection and malaria. Wound swab for microscopy ,culture and sensitivity, if there is wound dehiscence, and endo-cervical swab for microscopy, culture and sensitivity will be done on all the participants who have fever, marked abdominal tenderness, uterine sub-involution and foul smelling vaginal discharge to determine the cause of the infection.

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