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Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus - Trial NCT06421701

Access comprehensive clinical trial information for NCT06421701 through Pure Global AI's free database. This Phase 1 trial is sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University and is currently Not yet recruiting. The study focuses on Systemic Lupus Erythematosus. Target enrollment is 10 participants.

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NCT06421701
Phase 1
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06421701
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Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus
A Clinical Study of Anti-CD19 CAR-NK Cells in the Treatment of Refractory/Relapsed Systemic Lupus Erythematosus

Study Focus

anti-CD19 CAR-NK cells

Interventional

drug

Sponsor & Location

Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, China

Timeline & Enrollment

Phase 1

Jun 01, 2024

May 31, 2026

10 participants

Primary Outcome

The proportion of subjects with DLT,The proportion of subjects with adverse events

Summary

This study is a single-center, open-label, single-arm, dose-escalation trial. The aim of this
 study is to investigate the safety and efficacy of anti-CD19 CAR-NK cells in patients with
 refractory/relapsed systemic lupus erythematosus.

ICD-10 Classifications

Systemic lupus erythematosus
Systemic lupus erythematosus, unspecified
Lupus erythematosus
Systemic lupus erythematosus with organ or system involvement
Other forms of systemic lupus erythematosus

Data Source

ClinicalTrials.gov

NCT06421701

Non-Device Trial