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Resistance Exercise and Creatine in Colorectal Cancer - Trial NCT06420726

Access comprehensive clinical trial information for NCT06420726 through Pure Global AI's free database. This phase not specified trial is sponsored by University of South Carolina and is currently Recruiting. The study focuses on Colorectal Cancer. Target enrollment is 40 participants.

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NCT06420726
Recruiting
behavioral
Trial Details
ClinicalTrials.gov โ€ข NCT06420726
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Resistance Exercise and Creatine in Colorectal Cancer
The Feasibility and Acceptability of Resistance Training and Creatine Supplementation to Promote Physical Function in Sarcopenic Colorectal Cancer Survivors

Study Focus

Colorectal Cancer

Resistance Exercise

Interventional

behavioral

Sponsor & Location

University of South Carolina

Columbia, United States of America

Timeline & Enrollment

N/A

Sep 01, 2023

Jul 22, 2025

40 participants

Primary Outcome

Recruitment,Retention,Supplementation Adherence,Exercise Adherence

Summary

skeletal muscle mass and function, is prevalent in up to 60% of colorectal cancer patients.
 This condition arises from a combination of factors such as aging, inactivity, treatment side
 effects, malnutrition, tumor burden, and inflammation. Given this complexity, singular
 interventions may not be sufficient to address sarcopenia in this group.
 
 Creatine monohydrate, a compound vital for energy during exercise, has been extensively
 researched and proven safe and effective across various demographics, including older adults
 and clinical populations. Studies show that creatine enhances benefits from resistance
 training, indicating potential to counter muscle mass and function decline post-cancer
 treatment.
 
 This study aims to assess the feasibilty of combining creatine supplementation with
 resistance training versus resistance training alone in sarcopenic colorectal cancer
 survivors. A randomized controlled pilot trial will compare a 10-week program of resistance
 exercise plus creatine (EXSUPP) with resistance exercise alone (EXPLA), each with 20
 participants.

ICD-10 Classifications

Malignant neoplasm of colon
Malignant neoplasm: Descending colon
Malignant neoplasm: Colon, unspecified
Malignant neoplasm: Ascending colon
Malignant neoplasm: Overlapping lesion of colon

Data Source

ClinicalTrials.gov

NCT06420726

Non-Device Trial