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A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis - Trial NCT06418529

Access comprehensive clinical trial information for NCT06418529 through Pure Global AI's free database. This phase not specified trial is sponsored by Pfizer and is currently Not yet recruiting. The study focuses on Rheumatoid Arthritis. Target enrollment is 20000 participants.

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NCT06418529
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Trial Details
ClinicalTrials.gov โ€ข NCT06418529
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A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis
Comparative Effectiveness of New Initiators of Tofacitinib and Other Biologic/Targeted Synthetic DMARDs in Patients With Rheumatoid Arthritis

Study Focus

Rheumatoid Arthritis

tofacitinib

Observational

drug

Sponsor & Location

Pfizer

Timeline & Enrollment

N/A

May 15, 2024

Jul 15, 2024

20000 participants

Primary Outcome

Percentage of Participants With Clinical Disease Activity Index (CDAI) =10.0

Summary

The purpose of this study is to learn how different types of medicines may improve disease
 activity in people with rheumatoid arthritis (RA). RA is a kind of joint disease that causes
 pain and swelling.
 
 The study will look at data from a large, US-based group of RA patients who have taken the
 below medicines:
 
 - Tofacitinib
 
 - Abatacept
 
 - Tocilizumab or sarilumab
 
 The study will compare clinical disease activity scores of patients on the different
 medicines taken. The study will also decide whether some patient traits or disease factors
 play a role in how medicines may improve disease activity.

ICD-10 Classifications

Rheumatoid arthritis, unspecified
Other rheumatoid arthritis
Other specified rheumatoid arthritis
Rheumatoid arthritis with involvement of other organs and systems
Seronegative rheumatoid arthritis

Data Source

ClinicalTrials.gov

NCT06418529

Non-Device Trial