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Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms - Trial NCT06409338

Access comprehensive clinical trial information for NCT06409338 through Pure Global AI's free database. This phase not specified trial is sponsored by The First Affiliated Hospital with Nanjing Medical University and is currently Not yet recruiting. The study focuses on Parkinson Disease. Target enrollment is 32 participants.

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Trial Details
ClinicalTrials.gov โ€ข NCT06409338
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Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms
Research on the Brain Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation in Regulating PD Motor Symptoms

Study Focus

Parkinson Disease

Transcutaneous auricular vagus nerve stimulation (active๏ผ‰

Interventional

device

Sponsor & Location

The First Affiliated Hospital with Nanjing Medical University

Nanjing, China

Timeline & Enrollment

N/A

May 01, 2024

Sep 01, 2024

32 participants

Primary Outcome

alterations in functional topological properties within the cortex of bilateral cerebral hemispheres-Sigma,alterations in functional topological properties within the cortex of bilateral cerebral hemispheres-global efficiency (Eg),alterations in functional topological properties within the cortex of bilateral cerebral hemispheres-local efficiency (Eloc),alterations in functional topological properties within the cortex of bilateral cerebral hemispheres-nodal efficiency (Ne),changes in MEPs values,changes in RMT values,changes in CSP values,changes in SICI values,changes in ICF values

Summary

This study is a double blind comparative study exploring the neural underpinnings of taVNS
 modulating PD motor deficits. We hypothesize that taVNS might improve PD motor deficits by
 regulating the balance between excitation and inhibition in the primary motor cortex.

ICD-10 Classifications

Parkinson disease
Parkinsonism in diseases classified elsewhere
Dementia in Parkinson disease
Secondary parkinsonism
Secondary parkinsonism, unspecified

Data Source

ClinicalTrials.gov

NCT06409338

Device Trial