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Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study - Trial NCT06404840

Access comprehensive clinical trial information for NCT06404840 through Pure Global AI's free database. This Phase 2 trial is sponsored by Tianjin Medical University Cancer Institute and Hospital and is currently Recruiting. The study focuses on Pancreatic Cancer. Target enrollment is 30 participants.

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NCT06404840
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06404840
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Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study
Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases (PCLM): A Prospective, Single-Arm, Phase II Study

Study Focus

Pancreatic Cancer

nimotuzumab

Interventional

drug

Sponsor & Location

Tianjin Medical University Cancer Institute and Hospital

Tianjin, China

Timeline & Enrollment

Phase 2

May 06, 2022

May 31, 2026

30 participants

Primary Outcome

AEs

Summary

Patients with PCLM account for the majority of our department's pancreatic cancer cases and
 often have limited surgical options due to the aggressive nature of their tumors. For those
 with good performance status (ECOG PS 0-1), NCCN recommends gemcitabine + nab-paclitaxel
 (AG). Though nimotuzumab combined with gemcitabine improves survival, there remains scarce
 clinical data regarding its efficacy in conjunction with AG for treating PCLM. This study
 aims to evaluate the safety and efficacy of incorporating nimotuzumab with AG for PCLM.

ICD-10 Classifications

Malignant neoplasm of pancreas
Malignant neoplasm: Pancreas, unspecified
Malignant neoplasm: Head of pancreas
Malignant neoplasm: Tail of pancreas
Malignant neoplasm: Other parts of pancreas

Data Source

ClinicalTrials.gov

NCT06404840

Non-Device Trial