Pure Global

NoNO-42 Trial in Acute Ischemic Stroke Patients Selected for Thrombolysis With or Without Endovascular Thrombectomy - Trial NCT06403267

Access comprehensive clinical trial information for NCT06403267 through Pure Global AI's free database. This Phase 2 trial is sponsored by NoNO Inc. and is currently Not yet recruiting. The study focuses on Acute Ischemic Stroke. Target enrollment is 600 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

Free Database
Powered by Pure Global AI
840K+ Trials
NCT06403267
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06403267
View on ClinicalTrials.gov
Pure Global
DJ Fang

DJ Fang

MedTech Regulatory Expert

Need help with 30+ markets registration?

Pricing
NoNO-42 Trial in Acute Ischemic Stroke Patients Selected for Thrombolysis With or Without Endovascular Thrombectomy
A Multicentre, Prospective, Randomized, Open Label, Blinded-Endpoint, Placebo-controlled, Single-dose Trial to Determine the Efficacy and Safety of NoNO-42 in Participants With Acute Ischemic Stroke Selected for Thrombolysis With or Without Endovascular Thrombectomy (ACT-42 Trial)

Study Focus

Acute Ischemic Stroke

NoNO-42

Interventional

drug

Sponsor & Location

NoNO Inc.

Timeline & Enrollment

Phase 2

May 01, 2024

May 01, 2026

600 participants

Primary Outcome

Reducing global disability in participants with acute ischemic stroke (AIS)

Summary

ACT-42 is a domain of the ACT-GLOBAL platform (NCT06352632).
 
 This trial is a Phase 2b, multicenter, prospective, randomized, open label, blinded-endpoint
 (PROBE) controlled single-dose adaptive trial.
 
 A total of up to 600 male and female participants aged โ‰ฅ 45 to โ‰ค 90 years harboring an acute
 ischemic stroke who are eligible for an intravenous thrombolytic with or without endovascular
 thrombectomy therapy will be enrolled within 3 hours of stroke onset/last known well.

ICD-10 Classifications

Stroke, not specified as haemorrhage or infarction
Sequelae of stroke, not specified as haemorrhage or infarction
Cerebral infarction
Cerebral infarction, unspecified
Transient cerebral ischaemic attack, unspecified

Data Source

ClinicalTrials.gov

NCT06403267

Non-Device Trial