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Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition. - Trial NCT06401941

Access comprehensive clinical trial information for NCT06401941 through Pure Global AI's free database. This phase not specified trial is sponsored by Nicolaus Copernicus University and is currently Completed. The study focuses on Hyperbaric Oxygenation,Oxygen Toxicity,Antioxidants,Oxidative Stress. Target enrollment is 78 participants.

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NCT06401941
Completed
procedure
Trial Details
ClinicalTrials.gov โ€ข NCT06401941
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Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.
The Impact of Staying in Hyperbaric Oxygen Conditions on the Oxidant-antioxidant Balance and the Activities of Selected Lysosomal Enzymes

Study Focus

Hyperbaric Oxygen Therapy

Interventional

procedure

Sponsor & Location

Nicolaus Copernicus University

Bydgoszcz, Poland

Timeline & Enrollment

N/A

Apr 26, 2016

Dec 31, 2020

78 participants

Primary Outcome

Thiobarbituric acid reactive substances (TBARS),Malondialdehyde (MDA),Conjugated dienes (CD),Catalase (CAT),Superoxide dismutase (SOD),Glutathione peroxidase (GPx)

Summary

The aim of the research project was to investigate the effects of hyperbaric oxygen (HBO)
 treatment on the redox equilibrium in individuals with different pathological conditions.
 Both hyperbaric oxygenation and the pathological condition are associated with redox
 imbalance (oxidative stress), however, HBO is successfully used in the treatment of chronic
 wounds, e.g., diabetic foot syndrome, as well as in sudden and acute hearing loss, e.g.,
 acute acoustic trauma or idiopathic sudden sensorineural hearing loss.

ICD-10 Classifications

Toxic effect: Formaldehyde
Anoxic brain damage, not elsewhere classified
Toxic effect: Nitrogen oxides
Toxic effect: Carbon dioxide
Poisoning: Vitamins, not elsewhere classified

Data Source

ClinicalTrials.gov

NCT06401941

Non-Device Trial