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A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors - Trial NCT06394622

Access comprehensive clinical trial information for NCT06394622 through Pure Global AI's free database. This Phase 1 trial is sponsored by Fudan University and is currently Recruiting. The study focuses on Solid Tumor. Target enrollment is 12 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06394622
Phase 1
Recruiting
combination product
Trial Details
ClinicalTrials.gov โ€ข NCT06394622
View on ClinicalTrials.gov
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A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors

Study Focus

Solid Tumor

Cyclophosphamide + Fludarabine + Infusion of CAR-NKT Cells

Interventional

combination product

Sponsor & Location

Fudan University

Shanghai, China

Timeline & Enrollment

Phase 1

Apr 11, 2024

Jun 28, 2026

12 participants

Primary Outcome

ORR of CD70 CAR-NKT cell dynamics

Summary

This is a phase I, open-label, single-arm study conducted to evaluate the efficacy, safety
 and PK of CGC729 in the treatment of advanced malignant solid tumors.
 
 Condition or disease:advanced malignant solid tumors. Intervention/treatment:Biological: CD70
 CAR-NKT cells. Phase:I

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Carcinoma in situ, unspecified
Malignant neoplasm: Parametrium
Malignant neoplasm of other connective and soft tissue
Malignant neoplasm: Lip, unspecified, inner aspect

Data Source

ClinicalTrials.gov

NCT06394622

Non-Device Trial