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VIBE - Virtual Image Guided Brachytherapy Emulation for Locally Advanced Cervical Cancer (LACC) - Trial NCT06394297

Access comprehensive clinical trial information for NCT06394297 through Pure Global AI's free database. This phase not specified trial is sponsored by Fundacao Champalimaud and is currently Recruiting. The study focuses on Cervical Cancer. Target enrollment is 30 participants.

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NCT06394297
Recruiting
radiation
Trial Details
ClinicalTrials.gov โ€ข NCT06394297
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VIBE - Virtual Image Guided Brachytherapy Emulation for Locally Advanced Cervical Cancer (LACC)
A Phase I/II Study for Image Guided Stereotactic Body Radiation Therapy Boost for Definitive Treatment of Locally Advanced Cervical Cancer (LACC)

Study Focus

Cervical Cancer

SBRT

Interventional

radiation

Sponsor & Location

Fundacao Champalimaud

Lisboa, Portugal

Timeline & Enrollment

N/A

Aug 04, 2023

Aug 04, 2026

30 participants

Primary Outcome

Dosimetric Feasibility of SBRT boost,reproducibility of SBRT boost,Inter/intra fractional target motion,Adverse Events,Local control

Summary

This study will evaluate the role of SBRT with the aim to reproduce high dose rate
 brachytherapy (HDR BT) dose distribution by means of external beam radiotherapy in the
 radical treatment in patients with LACC. The study will employ devices to accurately
 reproduce pelvic anatomy and mitigate target motion and will make use of real-time online
 tracking.

ICD-10 Classifications

Severe cervical dysplasia, not elsewhere classified
Mild cervical dysplasia
Moderate cervical dysplasia
Carcinoma in situ: Cervix, unspecified
Cervical root disorders, not elsewhere classified

Data Source

ClinicalTrials.gov

NCT06394297

Non-Device Trial