Effect of CPAP on Respiratory Load in COPD - Trial NCT06390631
Access comprehensive clinical trial information for NCT06390631 through Pure Global AI's free database. This phase not specified trial is sponsored by State Key Laboratory of Respiratory Disease and is currently Recruiting. The study focuses on Chronic Obstructive Pulmonary Disease. Target enrollment is 19 participants.
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Study Focus
Sponsor & Location
State Key Laboratory of Respiratory Disease
Timeline & Enrollment
N/A
May 01, 2024
Jul 10, 2024
Primary Outcome
Diaphragm EMG,Lung volume,Intrinsic positive end expiratory pressure (PEEPi),Inspiratory pressure,Inspiratory work,Sensation of breathing effort
Summary
Both intrinsic positive end expiratory pressure (PEEPi) and dynamic hyperinflation are
 considered as inspiratory loads which increase work of breathing in patients with COPD. The
 application of extrinsic positive end expiratory pressure (PEEPe) supplied by CPAP has been
 claimed to reduce inspiratory load based on change in esophageal pressure which could be
 significantly affected by change in lung volume and airflow. The investigator hypothesized
 that CPAP could increase respiratory load because it increases lung volume.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06390631
Device Trial