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Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51 - Trial NCT06390098

Access comprehensive clinical trial information for NCT06390098 through Pure Global AI's free database. This Phase 1 trial is sponsored by Asceneuron S.A. and is currently Completed. The study focuses on Alzheimer Disease. Target enrollment is 3 participants.

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NCT06390098
Phase 1
Completed
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06390098
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Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51
A Phase 1, Open-Label, Positron Emission Tomography Study in Healthy Adult Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51 Following a Single Oral Dose

Study Focus

Alzheimer Disease

ASN51

Interventional

drug

Sponsor & Location

Asceneuron S.A.

London, United Kingdom

Timeline & Enrollment

Phase 1

Aug 09, 2021

Nov 02, 2021

3 participants

Primary Outcome

Pharmacodynamic (PD) change of [18F]-IMA601 regional total volume of distribution (VT) at each brain scan

Summary

This is a phase 1, open-label, PET study in healthy adult subjects to determine the
 relationship between plasma concentration and brain target occupancy of ASN51 following a
 single oral dose.

ICD-10 Classifications

Alzheimer disease
Alzheimer disease, unspecified
Other Alzheimer disease
Dementia in Alzheimer disease
Dementia in Alzheimer disease, unspecified

Data Source

ClinicalTrials.gov

NCT06390098

Non-Device Trial