Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy - Trial NCT06388486
Access comprehensive clinical trial information for NCT06388486 through Pure Global AI's free database. This phase not specified trial is sponsored by University Medical Center Goettingen and is currently Completed. The study focuses on Depression. Target enrollment is 63 participants.
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Study Focus
Sponsor & Location
University Medical Center Goettingen
Timeline & Enrollment
N/A
Jan 01, 2017
Jan 01, 2024
Primary Outcome
Change in depression
Summary
The goal of this observational study is to measure the levels of cytokine-induced
 transcription factor activation in a cohort of depressed inpatients undergoing psychotherapy.
 The study aims to answer the following main questions:
 
 - Do psychological traits (i.e.: social inhibition, negative affectivity, ...) affect the
 activation of immunomodulatory transcription factors (STAT3, NFkB) in depressed
 patients?
 
 - Are subjects with these psychological traits affected differently by psychotherapeutic
 intervention?
 
 Study subjects are assessed for their psychological and behavioral traits and receive
 psychotherapeutic care over several weeks during hospital treatment. Peripheral blood
 mononuclear cells are isolated from the study subjects, and activation of transcription
 factors is measured by flow cytometry.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06388486
Non-Device Trial