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Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS) - Trial NCT06385730

Access comprehensive clinical trial information for NCT06385730 through Pure Global AI's free database. This Phase 2 trial is sponsored by Shanghai Chest Hospital and is currently Not yet recruiting. The study focuses on Esophageal Cancer. Target enrollment is 60 participants.

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NCT06385730
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06385730
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Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)
Neoadjuvant PD-1 Blockade (Toripalimab) Monotherapy for Elderly Patients With Locally Advanced Resectable Esophageal Squamous Cell Carcinoma: a Phase II Trial

Study Focus

Esophageal Cancer

neoadjuvant anti-PD-1

Interventional

drug

Sponsor & Location

Shanghai Chest Hospital

Shanghai, China

Timeline & Enrollment

Phase 2

May 01, 2024

May 01, 2027

60 participants

Primary Outcome

MPR rate

Summary

The investigators will conduct a prospective phase 2 study to evaluate the efficacy and
 safety of neoadjuvant PD-1 blockade monotherapy with toripalimab in elderly patients with
 locally advanced resectable esophageal squamous cell carcinoma (ESCC).

ICD-10 Classifications

Carcinoma in situ: Oesophagus
Malignant neoplasm of oesophagus
Malignant neoplasm: Middle third of oesophagus
Malignant neoplasm: Overlapping lesion of oesophagus
Malignant neoplasm: Upper third of oesophagus

Data Source

ClinicalTrials.gov

NCT06385730

Non-Device Trial