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A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors - Trial NCT06384807

Access comprehensive clinical trial information for NCT06384807 through Pure Global AI's free database. This Phase 1/2 trial is sponsored by Pyramid Biosciences and is currently Not yet recruiting. The study focuses on Solid Tumor. Target enrollment is 170 participants.

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NCT06384807
Phase 1/2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06384807
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A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors
A Phase 1/2, First in Human, Dose Escalation and Dose Expansion Study of PBI-410 in Participants With Advanced Solid Tumors

Study Focus

Solid Tumor

PBI-410

Interventional

drug

Sponsor & Location

Pyramid Biosciences

Dallas,West Valley City,Fairfax, United States of America

Timeline & Enrollment

Phase 1/2

Apr 01, 2024

Feb 01, 2028

170 participants

Primary Outcome

Phase 1: Number of patients with adverse events (AEs),Phase 1: Recommended dose for expansion (RDE) and maximum tolerated dose (MTD),Phase 2: Objective Response Rate (ORR),Phase 2: Number of patients with AEs,Phase 2: Duration of Response (DoR)

Summary

This is a Phase 1/2, first in human (FIH), open-label, multicenter study of PBI-410 in
 participants with previously treated, advanced solid tumors.

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Carcinoma in situ, unspecified
Malignant neoplasm: Parametrium
Malignant neoplasm of other connective and soft tissue
Malignant neoplasm: Lip, unspecified, inner aspect

Data Source

ClinicalTrials.gov

NCT06384807

Non-Device Trial