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Tislelizumab Combined With Neoadjuvant Chemotherapy Used in the Perioperative Treatment. - Trial NCT06374901

Access comprehensive clinical trial information for NCT06374901 through Pure Global AI's free database. This Phase 2 trial is sponsored by Xiangdong Cheng and is currently Not yet recruiting. The study focuses on Gastric Cancer. Target enrollment is 134 participants.

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NCT06374901
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06374901
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Tislelizumab Combined With Neoadjuvant Chemotherapy Used in the Perioperative Treatment.
A Multicenter, Prospective Phase II Clinical Study of Tislelizumab in Combination With Chemotherapy for the Perioperative Treatment of Resectable Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma

Study Focus

Gastric Cancer

Tislelizumab

Interventional

drug

Sponsor & Location

Xiangdong Cheng

Zhejiang Cancer Hospital

Hangzhou, China

Timeline & Enrollment

Phase 2

Apr 25, 2024

Mar 31, 2028

134 participants

Primary Outcome

MRP (Main pathological response)

Summary

To evaluate the efficacy of Tislelizumab in combination with chemotherapy versus chemotherapy
 in neoadjuvant treatment of patients with MHC-II positive (IHCโ‰ฅ2+) and locally advanced
 gastric/gastroesophageal junction adenocarcinoma by evaluating the main pathologic response
 rate (MPR).

ICD-10 Classifications

Gastric ulcer
Malignant neoplasm of stomach
Malignant neoplasm: Body of stomach
Carcinoma in situ: Stomach
Malignant neoplasm: Stomach, unspecified

Data Source

ClinicalTrials.gov

NCT06374901

Non-Device Trial