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A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma - Trial NCT06371157

Access comprehensive clinical trial information for NCT06371157 through Pure Global AI's free database. This Phase 3 trial is sponsored by Akeso and is currently Not yet recruiting. The study focuses on Hepatocellular Carcinoma. Target enrollment is 469 participants.

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NCT06371157
Phase 3
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06371157
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A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma
A Phase III, Randomized, Double-blinded, Multicenter Study of Cadonilimab (AK104) + Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

Study Focus

Hepatocellular Carcinoma

AK104

Interventional

drug

Sponsor & Location

Akeso

Zhengzhou,Changsha,Nanjing,Taiyuan,Chengdu,Kunming,Hangzhou, China

Timeline & Enrollment

Phase 3

Jul 02, 2024

May 23, 2026

469 participants

Primary Outcome

Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1)

Summary

A study to evaluate cadonilimab (AK104) + lenvatinib in combination with transarterial
 chemoembolization (TACE) versus TACE in participants with incurable/non-metastatic
 hepatocellular carcinoma

ICD-10 Classifications

Malignant neoplasm: Hepatoblastoma
Malignant neoplasm: Liver cell carcinoma
Malignant neoplasm: Other specified carcinomas of liver
Malignant neoplasm: Liver, unspecified
Malignant neoplasm: Hepatic flexure

Data Source

ClinicalTrials.gov

NCT06371157

Non-Device Trial