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Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody - Trial NCT06364800

Access comprehensive clinical trial information for NCT06364800 through Pure Global AI's free database. This Phase 1 trial is sponsored by Beijing 302 Hospital and is currently Not yet recruiting. The study focuses on Hepatocellular Carcinoma. Target enrollment is 18 participants.

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NCT06364800
Phase 1
Not yet recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT06364800
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Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody
The Safety and Efficacy Assessment of Allogeneic ฮณฮด T Cells Combined With Targeted Therapy and Immunotherapy in Hepatocellular Carcinoma Patients

Study Focus

Hepatocellular Carcinoma

ฮณฮด T cells

Interventional

biological

Sponsor & Location

Beijing 302 Hospital

Timeline & Enrollment

Phase 1

Apr 26, 2024

Sep 26, 2026

18 participants

Primary Outcome

Safety evaluation: Incidence of Adverse events (AEs),Safety evaluation: Dose limited toxicity (DLTs),Efficacy evaluation: Objective Response Rate(ORR),Efficacy evaluation: Duration of Response(DOR),Efficacy evaluation: Progress Free Survival(PFS),Efficacy evaluation: Overall Survival (OS)

Summary

The purpose of this study is to evaluate the safety and efficacy of allogeneic ฮณฮด T cells
 combined with targeted therapy and PD-1 monoclonal antibody in patients with hepatocellular
 carcinoma resistant to PD-1 monoclonal antibody.
 
 Hepatocellular Carcinoma

ICD-10 Classifications

Malignant neoplasm: Hepatoblastoma
Malignant neoplasm: Liver cell carcinoma
Malignant neoplasm: Other specified carcinomas of liver
Malignant neoplasm: Liver, unspecified
Malignant neoplasm: Hepatic flexure

Data Source

ClinicalTrials.gov

NCT06364800

Non-Device Trial