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Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer - Trial NCT06363006

Access comprehensive clinical trial information for NCT06363006 through Pure Global AI's free database. This Phase 1 trial is sponsored by Peking Union Medical College Hospital and is currently Recruiting. The study focuses on Hepatocellular Carcinoma. Target enrollment is 40 participants.

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NCT06363006
Phase 1
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06363006
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Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer
Evaluation of the Efficacy and Safety of Cardonilimab Injection Combined With TKI as Second-line Treatment for Advanced Hepatocellular Carcinoma: A Single-arm, Open-label, Multicenter Real-world Clinical Study

Study Focus

Hepatocellular Carcinoma

TKI+Cardunilimab

Interventional

drug

Sponsor & Location

Peking Union Medical College Hospital

Beijing, China

Timeline & Enrollment

Phase 1

Mar 11, 2024

Jan 01, 2027

40 participants

Primary Outcome

ORR Full single-arm, open, multicenter prospective clinical study,Progression-free Survival (PFS)

Summary

The goal of this clinical trial is to evaluate the efficacy and safety of cardonilizumab
 injection combined with TKI in second-line treatment of advanced hepatocellular carcinoma.
 The main questions it aims to answer are:
 
 - Objective response rate (ORR) for evaluation
 
 - Disease Control Rate (DCR); Duration of relief (DoR); Progression free survival (PFS);
 Total survival time (OS); Safetyใ€‚

ICD-10 Classifications

Malignant neoplasm: Hepatoblastoma
Malignant neoplasm: Liver cell carcinoma
Malignant neoplasm: Other specified carcinomas of liver
Malignant neoplasm: Liver, unspecified
Malignant neoplasm: Hepatic flexure

Data Source

ClinicalTrials.gov

NCT06363006

Non-Device Trial