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Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC - Trial NCT06361758

Access comprehensive clinical trial information for NCT06361758 through Pure Global AI's free database. This Phase 2 trial is sponsored by Shanghai Zhongshan Hospital and is currently Not yet recruiting. The study focuses on Hepatocellular Carcinoma. Target enrollment is 30 participants.

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NCT06361758
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06361758
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Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC
Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC: A Single Arm, Multicenter, Phase II Trial. (SCALE)

Study Focus

Hepatocellular Carcinoma

Cadonilimab+Lenvatinib

Interventional

drug

Sponsor & Location

Shanghai Zhongshan Hospital

Shanghai,Guangzhou,Shanghai, China

Timeline & Enrollment

Phase 2

May 31, 2024

May 31, 2027

30 participants

Primary Outcome

Objective Response Rate (ORR) per RECIST v1.1

Summary

This is an open-label, multi-center, single-arm, phase II study to evaluate the efficacy and
 safety of lenvatinib in combination with cadonilimab as second-line therapy in subjects with
 advanced hepatocellular carcinoma (HCC) who failed first-line standard therapy of
 immunotheray and antiangiogenic therapy.

ICD-10 Classifications

Malignant neoplasm: Hepatoblastoma
Malignant neoplasm: Liver cell carcinoma
Malignant neoplasm: Other specified carcinomas of liver
Malignant neoplasm: Liver, unspecified
Malignant neoplasm: Hepatic flexure

Data Source

ClinicalTrials.gov

NCT06361758

Non-Device Trial