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The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients - Trial NCT06357806

Access comprehensive clinical trial information for NCT06357806 through Pure Global AI's free database. This phase not specified trial is sponsored by Beijing 302 Hospital and is currently Recruiting. The study focuses on Chronic Hepatitis B. Target enrollment is 45 participants.

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NCT06357806
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Trial Details
ClinicalTrials.govNCT06357806
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The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients
The Safety and Efficacy of PD-1 Antibody Combined With Pegylated Interferon-α Therapy to Promote the Clinical Cure in Nucleoside (Acid) Analogues-suppressed Chronic Hepatitis B Patients: A Protocol for the Prospective Pilot Study

Study Focus

Chronic Hepatitis B

Sintilimab

Interventional

drug

Sponsor & Location

Beijing 302 Hospital

Beijing, China

Timeline & Enrollment

N/A

May 01, 2024

Oct 30, 2025

45 participants

Primary Outcome

The rate of HBsAg loss at 24 weeks and 48 weeks.,Incidence of treatment-emergent adverse events/serious adverse events

Summary

This is a prospective, open-labled, randomized controlled study to assess efficacy and safety
 of treatment with Sintilimab (PDL-1 antibody) combined Peg-IFNα-2b in CHB patients on stable
 NAs treatment.

ICD-10 Classifications

Acute hepatitis B
Chronic viral hepatitis B without delta-agent
Acute delta-(super)infection in chronic hepatitis B
Chronic viral hepatitis B without delta-agent : other and unspecified phase
Chronic viral hepatitis B without delta-agent : immune-tolerant phase

Data Source

ClinicalTrials.gov

NCT06357806

Non-Device Trial