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A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight - Trial NCT06352892

Access comprehensive clinical trial information for NCT06352892 through Pure Global AI's free database. This Phase 1 trial is sponsored by Amgen and is currently Not yet recruiting. The study focuses on Obesity. Target enrollment is 20 participants.

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NCT06352892
Phase 1
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06352892
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A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight
A Phase 1, Open-label, Randomized, Parallel-group, Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 133 Administered Subcutaneously in Chinese Subjects With Obesity or Overweight

Study Focus

Obesity

AMG 133

Interventional

drug

Sponsor & Location

Amgen

Timeline & Enrollment

Phase 1

Apr 24, 2024

Sep 03, 2024

20 participants

Primary Outcome

Maximum Observed Plasma Concentration (Cmax) of AMG 133,Area Under the Plasma Concentration-time Curve (AUC) from Time Zero to the Last Quantifiable Concentration (AUClast) of AMG 133,AUC from Time Zero Extrapolated to Infinity (AUCinf) of AMG 133

Summary

The main objective of the study is to assess the pharmacokinetics (PK) of AMG 133 after a
 single subcutaneous (SC) administration in overweight or obese Chinese participants.

ICD-10 Classifications

Obesity
Other obesity
Obesity, unspecified
Obesity due to excess calories
Obesity and other hyperalimentation

Data Source

ClinicalTrials.gov

NCT06352892

Non-Device Trial