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Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors - Trial NCT06349837

Access comprehensive clinical trial information for NCT06349837 through Pure Global AI's free database. This Phase 1 trial is sponsored by Sichuan University and is currently Not yet recruiting. The study focuses on Solid Tumor. Target enrollment is 9 participants.

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NCT06349837
Phase 1
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06349837
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Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
Safety and Tolerability of Low Dose Radiotherapy Plus Concurrent Partial Stereotactic Ablative Radiotherapy (Eclipse-RT) and Tislelizumab in Patients With Bulky Tumors

Study Focus

Solid Tumor

Tislelizumab

Interventional

drug

Sponsor & Location

Sichuan University

Timeline & Enrollment

Phase 1

Apr 15, 2024

Mar 31, 2026

9 participants

Primary Outcome

Dose Limiting Toxicities

Summary

This is a 3+3 dose escalation phase I study which aims to evaluate the safety and
 tolerability of low dose radiotherapy (LDRT) plus concurrent partial Stereotactic Ablative
 Radiotherapy (SBRT) and Tislelizumab in Patients with bulky tumors who have failed standard
 therapy. At least 9 participants will be enrolled in this study.

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Carcinoma in situ, unspecified
Malignant neoplasm: Parametrium
Malignant neoplasm of other connective and soft tissue
Malignant neoplasm: Lip, unspecified, inner aspect

Data Source

ClinicalTrials.gov

NCT06349837

Non-Device Trial