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CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus - Trial NCT06349343

Access comprehensive clinical trial information for NCT06349343 through Pure Global AI's free database. This Phase 1 trial is sponsored by Wuhan Union Hospital, China and is currently Not yet recruiting. The study focuses on Systemic Lupus Erythematosus. Target enrollment is 20 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06349343
Phase 1
Not yet recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT06349343
View on ClinicalTrials.gov
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CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus
Clinical Study of the Safety and Efficacy of CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus

Study Focus

CD19/BCMA Hi-TCR-T cell therapy

Interventional

biological

Sponsor & Location

Wuhan Union Hospital, China

Timeline & Enrollment

Phase 1

Apr 01, 2024

Jan 01, 2026

20 participants

Primary Outcome

Safety and tolerability

Summary

The purpose of the study is to explore the safety and efficacy of cluster of differentiation
 19 (CD19)/B cell maturation antigen (BCMA) human leukocyte antigen (HLA)-independent T cell
 receptor (TCR) -T therapy in refractory/moderate-to-severe systemic lupus erythematosus(SLE).

ICD-10 Classifications

Systemic lupus erythematosus
Systemic lupus erythematosus, unspecified
Lupus erythematosus
Systemic lupus erythematosus with organ or system involvement
Other forms of systemic lupus erythematosus

Data Source

ClinicalTrials.gov

NCT06349343

Non-Device Trial