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A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer - Trial NCT06347705

Access comprehensive clinical trial information for NCT06347705 through Pure Global AI's free database. This Phase 2 trial is sponsored by Memorial Sloan Kettering Cancer Center and is currently Recruiting. The study focuses on Prostate Cancer. Target enrollment is 99 participants.

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NCT06347705
Phase 2
Recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT06347705
View on ClinicalTrials.gov
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A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer
Phase II Study Evaluating the Effects of Single Site Intratumoral Injections of Anti-CD40 Agonist Antibody (2141-V11) Given as Monotherapy Prior to Radical Prostatectomy to Men With Intermediate Risk Disease and in Combination With Androgen Deprivation Therapy for Those With High Risk Localized and Low Volume Metastatic Disease

Study Focus

Prostate Cancer

2141-V11 Antibody

Interventional

biological

Sponsor & Location

Memorial Sloan Kettering Cancer Center

Basking Ridge,Middletown,Montvale,Commack,Harrison,New York,Rockville Centre, United States of America

Timeline & Enrollment

Phase 2

Mar 28, 2024

Mar 28, 2029

99 participants

Primary Outcome

Number of participants with a complete response or minimal residual disease.

Summary

The purpose of this study is to see whether combining 2141-V11 with various standard
 treatments is an effective treatment approach for prostate cancer. 2141-V11 works by
 activating the immune system to find and kill cancer cells. Researchers will look at whether
 this treatment approach is able to completely get rid of cancer in participants, and they
 will check for the presence of minimal residual disease (MRD) in participants. MRD is a small
 number of cancer cells that can be detected in the body after treatment.

ICD-10 Classifications

Malignant neoplasm of prostate
Hyperplasia of prostate
Disorder of prostate, unspecified
Other disorders of prostate
Carcinoma in situ: Prostate

Data Source

ClinicalTrials.gov

NCT06347705

Non-Device Trial