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To Evaluate the Safety and Tolerability of Carbognilumab Combined With Chemotherapy as the First-line Treatment for Patients With KEAP1 Mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer (NSCLC) - Trial NCT06341660

Access comprehensive clinical trial information for NCT06341660 through Pure Global AI's free database. This Phase 2 trial is sponsored by Guangzhou Institute of Respiratory Disease and is currently Recruiting. The study focuses on Non-small Cell Lung Cancer. Target enrollment is 30 participants.

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NCT06341660
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06341660
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To Evaluate the Safety and Tolerability of Carbognilumab Combined With Chemotherapy as the First-line Treatment for Patients With KEAP1 Mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer (NSCLC)
A Single-arm Pilot Study of Patients With Advanced or Postoperative Recurrent Non-small Cell Lung Cancer (NSCLC) With KEAP1 Mutation Treated With Carbonizumab Combined With Chemotherapy as the First-line Treatment

Study Focus

cadonilimab

Interventional

drug

Sponsor & Location

Guangzhou Institute of Respiratory Disease

Guangdong, China

Timeline & Enrollment

Phase 2

May 25, 2023

Jul 01, 2025

30 participants

Primary Outcome

Safety assessments and ORR

Summary

To evaluate the safety and tolerability of carbognilumab combined with chemotherapy as
 first-line treatment in patients with KeAP1-mutated advanced or postoperative recurrent
 non-small cell lung cancer.

ICD-10 Classifications

Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Middle lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06341660

Non-Device Trial