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BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus - Trial NCT06340750

Access comprehensive clinical trial information for NCT06340750 through Pure Global AI's free database. This Phase 1 trial is sponsored by Luminary Therapeutics and is currently Not yet recruiting. The study focuses on Systemic Lupus Erythematosus. Target enrollment is 18 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06340750
Phase 1
Not yet recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT06340750
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BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
A Phase I Study of BAFF CAR-T Cells (LMY-920) for Treatment of Systemic Lupus Erythematosus

Study Focus

LMY-920

Interventional

biological

Sponsor & Location

Luminary Therapeutics

Timeline & Enrollment

Phase 1

Jun 01, 2024

Apr 15, 2026

18 participants

Primary Outcome

Safety of the Treatment,Recommended Phase 2 Dose (RP2D)

Summary

This phase 1 study seeks to examine the safety and recommended phase 2 dose (RP2D) of
 BAFF-ligand CAR-T cells (LMY-920) in adult patients with refractory systemic lupus
 erythematosus (SLE). It is hypothesized that BAFF CAR-T cells will be safe and will improve
 SLE disease activity scores.

ICD-10 Classifications

Systemic lupus erythematosus
Systemic lupus erythematosus, unspecified
Lupus erythematosus
Systemic lupus erythematosus with organ or system involvement
Other forms of systemic lupus erythematosus

Data Source

ClinicalTrials.gov

NCT06340750

Non-Device Trial