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Pre-Transplant INCBB099280 for Hepatocellular Carcinoma (HCC) - Trial NCT06337162

Access comprehensive clinical trial information for NCT06337162 through Pure Global AI's free database. This Phase 1 trial is sponsored by Abramson Cancer Center at Penn Medicine and is currently Not yet recruiting. The study focuses on Hepatocellular Carcinoma. Target enrollment is 15 participants.

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NCT06337162
Phase 1
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06337162
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Pre-Transplant INCBB099280 for Hepatocellular Carcinoma (HCC)
A Pilot Study of Neoadjuvant INCB099280 in Patients With Hepatocellular Carcinoma Awaiting Liver Transplant

Study Focus

Hepatocellular Carcinoma

INCB099280

Interventional

drug

Sponsor & Location

Abramson Cancer Center at Penn Medicine

Philadelphia, United States of America

Timeline & Enrollment

Phase 1

May 01, 2024

Sep 01, 2028

15 participants

Primary Outcome

Acute Cellular Rejection of Liver Transplant Attributed to Study Therapy

Summary

This is a pilot safety study of the oral PD-L1 inhibitor INCB099280 in patients with HCC
 awaiting liver transplant.

ICD-10 Classifications

Malignant neoplasm: Hepatoblastoma
Malignant neoplasm: Liver cell carcinoma
Malignant neoplasm: Other specified carcinomas of liver
Malignant neoplasm: Liver, unspecified
Malignant neoplasm: Hepatic flexure

Data Source

ClinicalTrials.gov

NCT06337162

Non-Device Trial