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A Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors With Resectable Disease With Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H) - Trial NCT06331598

Access comprehensive clinical trial information for NCT06331598 through Pure Global AI's free database. This Phase 2 trial is sponsored by Hoffmann-La Roche and is currently Recruiting. The study focuses on Solid Tumors. Target enrollment is 40 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06331598
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06331598
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A Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors With Resectable Disease With Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)
A Phase II, Open Label, Randomized, Non-Comparative Cohorts Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors With Resectable Disease With Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

Study Focus

Solid Tumors

Atezolizumab

Interventional

drug

Sponsor & Location

Hoffmann-La Roche

Barcelona,Madrid,Sevilla, Spain

Timeline & Enrollment

Phase 2

Jul 30, 2024

Sep 20, 2029

40 participants

Primary Outcome

Disease Free Survival (DFS) Rate at 24 Months

Summary

This study is being conducted to evaluate efficacy parameters (disease free survival [DFS]
 and overall survival [OS]) of atezolizumab and atezolizumab in combination with tiragolumab
 in TMB-H or MSI-H as adjuvant treatment after standard radical intended treatment in
 participants with intermediate-high risk of recurrence.

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Malignant neoplasm of other connective and soft tissue
Carcinoma in situ, unspecified
Malignant neoplasms
Malignant neoplasm: Parametrium

Data Source

ClinicalTrials.gov

NCT06331598

Non-Device Trial