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Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA. - Trial NCT06328179

Access comprehensive clinical trial information for NCT06328179 through Pure Global AI's free database. This phase not specified trial is sponsored by Huai'an First People's Hospital and is currently Recruiting. The study focuses on Acute Myeloid Leukemia. Target enrollment is 34 participants.

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NCT06328179
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Trial Details
ClinicalTrials.govNCT06328179
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Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA.
Clinical Study Protocol for the Treatment of Newly Diagnosed and Relapsed/Refractory Acute Myeloid Leukemia With KMT2A Gene Abnormalities Using VHEA(Venetoclax With Homoharringtonine,Etoposide,Cytarabine)

Study Focus

Acute Myeloid Leukemia

Venetoclax 100 mg d1,200 mg d2,400 mg d3-14;

Interventional

drug

Sponsor & Location

Huai'an First People's Hospital

Huai'an, China

Timeline & Enrollment

N/A

May 24, 2022

Dec 30, 2027

34 participants

Primary Outcome

Overall response rate,ORR

Summary

This study is a clinical trial aimed at evaluating the efficacy and safety of the
 VHEA(Venetoclax with Homoharringtonine,Etoposide,Cytarabine)regimen in the treatment of newly
 diagnosed and relapsed/refractory acute myeloid leukemia (AML) with MLL gene abnormalities.
 
 This study includes the induction and consolidation phases of AML treatment.

ICD-10 Classifications

Myeloid leukaemia
Acute myeloblastic leukaemia [AML]
Myeloid leukaemia, unspecified
Acute myelomonocytic leukaemia
Acute myeloid leukaemia with 11q23-abnormality

Data Source

ClinicalTrials.gov

NCT06328179

Non-Device Trial