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The Epigenetic Regulatory Role of P-element Induced Wimpy Testis (Piwi) Interacting RNA-823 (piR-823) in Ovarian Cancer Progression - Trial NCT06320418

Access comprehensive clinical trial information for NCT06320418 through Pure Global AI's free database. This phase not specified trial is sponsored by Ain Shams University and is currently Recruitment Completed. The study focuses on Ovarian Cancer. Target enrollment is 56 participants.

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NCT06320418
Recruitment Completed
Trial Details
ClinicalTrials.gov โ€ข NCT06320418
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The Epigenetic Regulatory Role of P-element Induced Wimpy Testis (Piwi) Interacting RNA-823 (piR-823) in Ovarian Cancer Progression
The Epigenetic Regulatory Role of P-element Induced Wimpy Testis (Piwi) Interacting RNA-

Study Focus

Ovarian Cancer

Observational

Sponsor & Location

Ain Shams University

Cairo, Egypt

Timeline & Enrollment

N/A

Jun 15, 2022

Jun 01, 2024

56 participants

Primary Outcome

Association of piR-823 expression with ovarian cancer progression

Summary

Ovarian cancer (OC) has one of the highest mortality rates for female malignant tumors,
 attributed to advanced cancer stages upon diagnosis as well as a high recurrence rate.
 Piwi-interacting RNA-823 (piR-823) is a single-stranded non-protein coding RNA (ncRNA) star
 molecule in epigenetics research. Extensive cellular regulatory functions and aberrant
 expression of piR-823 have been implicated in carcinogenesis. Therefore, the findings of
 piwi-ncRNA dysregulated-expression in OC Egyptian female patients' cohort could be employed
 as a potential novel mechanism for OC precision, a step toward ncRNA-precision

ICD-10 Classifications

Malignant neoplasm of ovary
Secondary malignant neoplasm of ovary
Benign neoplasm of ovary
Ovarian pregnancy
Ovarian dysfunction

Data Source

ClinicalTrials.gov

NCT06320418

Non-Device Trial